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复发性腰椎间盘突出症后路腰椎椎间融合术后的长期临床疗效及疼痛评估

Long-Term Clinical Outcomes and Pain Assessment after Posterior Lumbar Interbody Fusion for Recurrent Lumbar Disc Herniation.

作者信息

Yang Yalin, Yan Xu, Li Wenhui, Sun Weizong, Wang Kai

机构信息

Department of Orthopedics, The Second Hospital of Tianjin Medical University, Tianjin, China.

Department of Orthopedics Emergency, Tianjin Hospital, Tianjin, China.

出版信息

Orthop Surg. 2020 Jun;12(3):907-916. doi: 10.1111/os.12706. Epub 2020 Jun 3.

Abstract

OBJECTIVES

The aim of this study was to investigate the long term effects of posterior lumbar interbody fusion (PLIF), applied after recurrent lumbar disc herniation (rLDH), on pain relief and clinical outcome improvement.

METHODS

The current study is a retrospective study. We observed 22 cases from 85 patients that had undergone PLIF during February 2003 to October 2012 and all patients were followed for at least 5 years. The average age of those patients were 53 years, among them there were eight men and 14 women. Plain radiography and dynamic plain films were obtained, pre-operation, for every patient. Magnetic resonance imaging (MRI) or computed tomography (CT) was conducted to confirm the diagnosis of rLDH before the operation. All surgeries were performed from posterior approach by the same surgeon using PLIF. Quality of life (QOL) and clinical outcomes were assessed by Numerical Rating Scale (NRS), Japanese Orthopaedic Association (JOA) scoring system, and Oswestry Disability Index (ODI) before revision surgery and at 1 week, 3 months, 12 months, and 24 months postoperative. These were also examined every time they came back to the hospital for a review.

RESULTS

All patients were discharged and no serious comorbidities occurred. Three cases with wound infections and one case with dural laceration were cured and discharged. The end point of follow-up was August 2018 and the mean follow-up after revision surgery was 85 months. There were significant differences in NRS. It decreased from 7.32 ± 1.17 to 2.77 ± 1.31 (P < 0.05). The mean postoperative NRS score was 2.27 ± 1.48 (P < 0.05), 1.90 ± 1.51 (P < 0.05), and 2.36 ± 1.36 (P < 0.05) at 3, 12, and 24 months after surgery. There were no statistically significant differences (P > 0.05) in ODI scores. The average JOA score improved from 5.00 ± 1.08 to 8.18 ± 1.59 (P < 0.05) 1 week after revision surgery. RR was between 50% and 70%. Overall satisfaction rates were beyond 80%. Only one patient required subsequent lumber surgery during the follow-up period.

CONCLUSION

If surgical indications are mastered, undergoing PLIF after rLDH may induce efficient pain relief and major improvements in clinical outcome scores, as well as quality of life scores.

摘要

目的

本研究旨在探讨复发性腰椎间盘突出症(rLDH)后应用后路腰椎椎间融合术(PLIF)对缓解疼痛及改善临床疗效的长期影响。

方法

本研究为回顾性研究。我们观察了2003年2月至2012年10月期间接受PLIF手术的85例患者中的22例,所有患者均随访至少5年。这些患者的平均年龄为53岁,其中男性8例,女性14例。每位患者术前均拍摄了X线平片和动态平片。术前进行磁共振成像(MRI)或计算机断层扫描(CT)以确诊rLDH。所有手术均由同一位外科医生经后路采用PLIF进行。在翻修手术前、术后1周、3个月、12个月和24个月,采用数字评分量表(NRS)、日本骨科协会(JOA)评分系统和Oswestry功能障碍指数(ODI)评估生活质量(QOL)和临床疗效。每次患者回医院复查时也进行这些检查。

结果

所有患者均出院,未发生严重合并症。3例伤口感染患者和1例硬脊膜撕裂患者均治愈出院。随访终点为2018年8月,翻修手术后的平均随访时间为85个月。NRS有显著差异。从7.32±1.17降至2.77±1.31(P<0.05)。术后3、12和24个月时,平均NRS评分分别为2.27±1.48(P<0.05)、1.90±1.51(P<0.05)和2.36±1.36(P<0.05)。ODI评分无统计学显著差异(P>0.05)。翻修手术后1周,平均JOA评分从5.00±1.08提高到8.18±1.59(P<0.05)。缓解率在50%至70%之间。总体满意率超过80%。随访期间仅1例患者需要后续腰椎手术。

结论

如果掌握手术指征,rLDH后行PLIF可能有效缓解疼痛,显著改善临床疗效评分及生活质量评分。

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