Han Ga Hee, Han Dong Jin, Lee Jong Hyun, Byeon Suk Ho, Shin Joo Youn
Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2020 Jun;34(3):235-241. doi: 10.3341/kjo.2019.0126.
To investigate the tomographic structural changes in the retinal layers after internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (ERM).
Sixty-nine eyes treated with vitrectomy and ILM peeling for idiopathic ERM were analyzed. Parafoveal retinal thickness was measured at baseline and 6 months after surgery.
Total retinal thickness decreased significantly in the nasal and temporal subfields after surgery ( < 0.001), whereas the inner nuclear layer and outer nuclear layer showed nasal thickening (all, < 0.001). The postoperative temporal/nasal subfield thickness ratio of each layer was significantly lower than that of fellow eyes. Eyes with larger ILM peeling showed a significantly lower temporal/nasal subfield thickness ratio ( = 0.033) than those with smaller sizes.
The retinal thickness of each layer showed anatomical changes from ILM peeling and ERM removal. Nasal parafoveal thickening and temporal thinning occurred in the inner retinal architecture, which might be affected by ILM peeling size.
研究特发性视网膜前膜（ERM）行内界膜（ILM）剥除术后视网膜各层的断层结构变化。
分析69只接受玻璃体切除术及ILM剥除术治疗特发性ERM的患眼。在基线期及术后6个月测量黄斑旁视网膜厚度。
术后鼻侧和颞侧子区域的视网膜总厚度显著降低（<0.001），而内核层和外核层出现鼻侧增厚（均<0.001）。各层术后颞侧/鼻侧子区域厚度比显著低于对侧眼。ILM剥除范围较大的患眼颞侧/鼻侧子区域厚度比显著低于剥除范围较小的患眼（=0.033）。
各层视网膜厚度因ILM剥除和ERM去除而出现解剖学变化。视网膜内层结构出现黄斑旁鼻侧增厚和颞侧变薄，这可能受ILM剥除范围的影响。
