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[真实世界研究中16856例老年患者速效救心丸的临床特征及联合用药情况]

[Clinical characteristics and combined medication of Suxiao Jiuxin Pills in 16 856 elderly patients in real world study].

作者信息

Sun Lin-Xi, Li Yuan-Yuan, Xie Yan-Ming, Wang Huan, Zhuang Yan

机构信息

Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences Beijing 100700, China Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing 100091, China.

Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences Beijing 100700, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2020 May;45(10):2335-2342. doi: 10.19540/j.cnki.cjcmm.20200302.501.

DOI:10.19540/j.cnki.cjcmm.20200302.501
PMID:32495590
Abstract

From 2001 to 2015, medical data of 16 856 elderly patients aged 65 years and over who used Suxiao Jiuxin Pills in the information system of 37 tertiary A-level hospitals were collected. After standardized analysis, it was found that the average age of 16 856 elderly patients was 72.48 years, and the main admission departments were department of cardiology(19.30%) and geriatric department(9.77%). Generally, 61.96% of the degree of illness is average, and the average hospitalized days were 16.16 days; 47.97% of the patients were diagnosed as coronary heart disease by Western medicine, and 5.86% of the patients were diagnosed as Qi deficiency and blood stasis; The more common combination of Western medicine was isosorbide nitrate(61.15%), Aspirin Enteric Coated Tablets(50.77%) and Gansu(36.88%), the combination of traditional Chinese medicine is Compound Danshen Dropping Pills/Tablets(19.13%), Xuesaitong Capsules/Injection(15.01%), Shexiang Baoxin Pills(12.29%); the commonly used Western medicine is vasodilator(78.39%), Chinese medicine is Huoxue Huayu(82.04%), and the commonly used Western medicine is Aaspirin Enteric Coated Tablets+Isosorbide Nitrate. The author intends to explore the valuable clinical characteristics and the clues of the combined medication scheme, and find that the application of Suxiao Jiuxin Pills basically conforms to the instructions, conforms to the characteristics of the elderly with many common diseases and complicated concurrent diseases; the combination of drugs and the indications-coronary heart disease guidelines are consistent, with certain rules to follow, and expand the recognition of the clinical application of Suxiao Jiuxin Pills, and provide clinical diagnosis and treatment ideas.

摘要

收集2001年至2015年期间,37家三级甲等医院信息系统中16856例65岁及以上使用速效救心丸的老年患者的医学数据。经标准化分析,发现16856例老年患者的平均年龄为72.48岁,主要收治科室为心内科(19.30%)和老年科(9.77%)。一般病情程度平均的占61.96%,平均住院天数为16.16天;47.97%的患者西医诊断为冠心病,5.86%的患者中医诊断为气虚血瘀;西医联合用药较常见的是硝酸异山梨酯(61.15%)、阿司匹林肠溶片(50.77%)和丹参(36.88%),中药联合用药是复方丹参滴丸/片(19.13%)、血塞通胶囊/注射液(15.01%)、麝香保心丸(12.29%);常用西药为血管扩张剂(78.39%),中药为活血化瘀药(82.04%),常用西药联合为阿司匹林肠溶片+硝酸异山梨酯。作者旨在探索有价值的临床特征及联合用药方案线索,发现速效救心丸的应用基本符合说明书,符合老年患者常见病多、合并症复杂的特点;联合用药与冠心病指南适应证一致,有一定规律可循,拓展了对速效救心丸临床应用的认识,为临床诊疗提供思路。

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