Deng Huajuan, Tian Chang, Gao Zhiwen, Chen Shu-Wei, Li Yang, Zhang Qingmiao, Yu Ruijin, Wang Jinyi
College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100, PR China.
Analyst. 2020 Jul 21;145(14):4931-4936. doi: 10.1039/d0an00208a. Epub 2020 Jun 4.
Iron (Fe) is one of the most essential elements in the human body; deficiency or overdose of Fe may have adverse effects on human health and immunity. Hence, it is essential to establish a sensitive and selective method for ion detection. In this study, novel green fluorescent N-doped carbon dots (N-CDs) were prepared with caffeic acid as the carbon source via a simple hydrothermal method. The solution of the as-prepared N-CDs exhibits 21.5% quantum yield, good salt stability, excellent water solubility, low cytotoxicity and good photobleaching resistance. The N-CDs can be used as a fluorescent probe for the detection of Fe ions in aqueous solutions and bioimaging in living cells.
铁（Fe）是人体中最重要的元素之一；铁缺乏或过量可能会对人体健康和免疫力产生不利影响。因此，建立一种灵敏且具有选择性的离子检测方法至关重要。在本研究中，以咖啡酸为碳源，通过简单的水热法制备了新型绿色荧光氮掺杂碳点（N-CDs）。所制备的N-CDs溶液具有21.5%的量子产率、良好的盐稳定性、优异的水溶性、低细胞毒性和良好的抗光漂白性。N-CDs可用作水溶液中检测铁离子以及活细胞生物成像的荧光探针。
