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一项在马哈拉施特拉邦浦那的一家三级护理医院中确诊的 COVID-19 病例的流行病学研究。

An epidemiological study of laboratory confirmed COVID-19 cases admitted in a tertiary care hospital of Pune, Maharashtra.

机构信息

Dean and Professor and Head, B.J. Govt. Medical College, Pune, Maharashtra, India.

Associate Professor, B.J. Govt. Medical College, Pune, Maharashtra, India.

出版信息

Indian J Public Health. 2020 Jun;64(Supplement):S183-S187. doi: 10.4103/ijph.IJPH_522_20.

DOI:10.4103/ijph.IJPH_522_20
PMID:32496252
Abstract

BACKGROUND

India has reported more than 70,000 cases and 2000 deaths. Pune is the second city in the Maharashtra state after Mumbai to breach the 1000 cases. Total deaths reported from Pune were 158 with a mortality of 5.7%. To plan health services, it is important to learn lessons from early stage of the outbreak on course of the disease in a hospital setting.

OBJECTIVES

To describe the epidemiological characteristics of the outbreak of COVID-19 in India from a tertiary care hospital.

METHODS

This was a hospital-based cross-sectional study which included all admitted laboratory confirmed COVID19 cases from March 31, to April 24, 2020. The information was collected in a predesigned pro forma which included sociodemographic data, duration of stay, family background, outcome, etc., by trained staff after ethics approval. Epi Info7 was used for data analysis.

RESULTS

Out of the total 197 cases, majority cases were between the ages of 31-60 years with slight male preponderance. Majority of these cases were from the slums. Breathlessness was the main presenting symptom followed by fever and cough. More than 1/5 of patients were asymptomatic from exposure to admission. The case fatality rate among the admitted cases was 29.4%. Comorbidity was one of the significant risk factors for the progression of disease and death (odds ratio [OR] = 16.8, 95% confidence interval [CI] = 7.0 - 40.1, P < 0.0001).

CONCLUSION

Mortality was higher than the national average of 3.2%; comorbidity was associated with bad prognosis.

摘要

背景

印度报告了超过 7 万例病例和 2000 例死亡。浦那是马哈拉施特拉邦继孟买之后第二个突破 1000 例的城市。浦那报告的总死亡人数为 158 人,死亡率为 5.7%。为了规划卫生服务,从医院环境中疾病的早期阶段吸取教训对于了解疾病的进程非常重要。

目的

描述印度一家三级保健医院 COVID-19 暴发的流行病学特征。

方法

这是一项基于医院的横断面研究,纳入了 2020 年 3 月 31 日至 4 月 24 日期间所有经实验室确诊的 COVID19 住院病例。在获得伦理批准后,由经过培训的工作人员使用预先设计的表格收集包括社会人口统计学数据、住院时间、家庭背景、结局等信息。Epi Info7 用于数据分析。

结果

在总共 197 例病例中,大多数病例年龄在 31-60 岁之间,男性略占优势。这些病例大多来自贫民窟。呼吸困难是主要的首发症状,其次是发热和咳嗽。超过 1/5 的患者从接触到入院时无症状。住院病例的病死率为 29.4%。合并症是疾病进展和死亡的一个重要危险因素(比值比[OR] = 16.8,95%置信区间[CI] = 7.0-40.1,P<0.0001)。

结论

死亡率高于全国平均水平 3.2%;合并症与不良预后相关。

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