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HIV、HPV 和沙眼衣原体:对男性生育力的影响。

HIV, HPV and Chlamydia trachomatis: impacts on male fertility.

出版信息

JBRA Assist Reprod. 2020 Oct 6;24(4):492-497. doi: 10.5935/1518-0557.20200020.

Abstract

Sexually transmitted diseases (STDs) are pathologies that have viruses, bacteria, protozoa and fungi as infectious agents, affecting millions of people worldwide and causing physical and psychological consequences for the carrier. Some of these infections such as HIV, HPV and Chlamydia trachomatis may present an asymptomatic phase, making the diagnosis difficult, which is often only performed when the couple looks for infertility treatment after not achieving spontaneous pregnancy. Infertility affects 15% of couples, 50% of cases are male-related, and it is estimated that STDs, which interfere with the physiology of the male reproductive system and may impair semen in parameters such as motility, concentration, morphology and number, cause 15% of male infertility cases. Since STDs treatments are increasing the expectation and quality of life of infected patients, discussing issues such as sexuality and reproduction is of great importance in clarifying unknown facts. This paper aims to discuss how the infectious processes associated with HIV, HPV and Chlamydia trachomatis can interfere with semen quality causing male infertility without apparent cause.

摘要

性传播疾病(STDs)是由病毒、细菌、原生动物和真菌等感染因子引起的疾病,影响着全球数百万人,并给携带者带来身体和心理上的后果。其中一些感染,如 HIV、HPV 和沙眼衣原体,可能会出现无症状阶段,使得诊断变得困难,通常只有在夫妇未能自然怀孕后寻求不孕治疗时才进行诊断。不孕影响了 15%的夫妇,其中 50%的病例与男性有关,据估计,干扰男性生殖系统生理学并可能损害精子运动能力、浓度、形态和数量等参数的性传播疾病,导致 15%的男性不孕病例。由于 STD 治疗可以提高感染患者的预期寿命和生活质量,因此讨论与性行为和生殖相关的问题对于澄清未知事实非常重要。本文旨在讨论与 HIV、HPV 和沙眼衣原体相关的感染过程如何在没有明显原因的情况下干扰精液质量,导致男性不孕。

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