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在中高湿度下,人工唾液和组织培养液中 SARS-CoV-2 的实验气溶胶存活情况。

Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tissue culture media at medium and high humidity.

机构信息

Chemical Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Wiltshire, UK.

出版信息

Emerg Microbes Infect. 2020 Dec;9(1):1415-1417. doi: 10.1080/22221751.2020.1777906.

DOI:10.1080/22221751.2020.1777906
PMID:32496967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7473326/
Abstract

SARS-CoV-2, the causative agent of the COVID-19 pandemic, may be transmitted via airborne droplets or contact with surfaces onto which droplets have deposited. In this study, the ability of SARS-CoV-2 to survive in the dark, at two different relative humidity values and within artificial saliva, a clinically relevant matrix, was investigated. SARS-CoV-2 was found to be stable, in the dark, in a dynamic small particle aerosol under the four experimental conditions we tested and viable virus could still be detected after 90 minutes. The decay rate and half-life was determined and decay rates ranged from 0.4 to 2.27 % per minute and the half lives ranged from 30 to 177 minutes for the different conditions. This information can be used for advice and modelling and potential mitigation strategies.

摘要

SARS-CoV-2,COVID-19 大流行的病原体,可能通过空气飞沫传播或接触到有飞沫沉积的表面。在这项研究中,研究了 SARS-CoV-2 在黑暗中、两种不同相对湿度值下以及在临床相关基质人工唾液中的存活能力。研究发现,SARS-CoV-2 在我们测试的四种实验条件下,在动态小颗粒气溶胶中黑暗稳定,90 分钟后仍可检测到存活病毒。确定了衰减率和半衰期,不同条件下的衰减率范围为每分钟 0.4%至 2.27%,半衰期范围为 30 分钟至 177 分钟。这些信息可用于提供建议和建模以及潜在的缓解策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177e/7473326/d12d3cc0dd24/TEMI_A_1777906_F0001_OB.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177e/7473326/d12d3cc0dd24/TEMI_A_1777906_F0001_OB.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/177e/7473326/d12d3cc0dd24/TEMI_A_1777906_F0001_OB.jpg

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