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花粉可能是抑制流感样流行的季节性因素。荷兰对 2016-2019 年花粉计数、花粉热和流感样发病率之间的反比关系进行的研究。

Pollen likely seasonal factor in inhibiting flu-like epidemics. A Dutch study into the inverse relation between pollen counts, hay fever and flu-like incidence 2016-2019.

机构信息

Open University Netherlands, De Liesbosch 12d, 3439LC Nieuwegein, the Netherlands.

出版信息

Sci Total Environ. 2020 Jul 20;727:138543. doi: 10.1016/j.scitotenv.2020.138543. Epub 2020 Apr 17.

DOI:10.1016/j.scitotenv.2020.138543
PMID:32498207
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7162772/
Abstract

There is uncertainty if current models for the Covid-19 pandemic should already take into account seasonality. That is because current environmental factors do not provide a powerful explanation of such seasonality, especially given climate differences between countries with moderate climates. It is hypothesized that one major factor is overlooked: pollen count. Pollen are documented to invoke strong immune responses and might create an environmental factor that makes it more difficult for flu-like viruses to survive outside a host. This Dutch study confirms that there is a (highly) significant inverse correlation between pollen count and weekly changes in medical flu consults, and that there is a highly significant inverse correlation between hay fever incidence, as measured by prescribed medication revenues, and weekly flu consults. This supports the idea that pollen are a direct or indirect factor in the seasonality of flu-like epidemics. If seasonality will be observed during the covid-19 spread as well, it is not unlikely that pollen play a role.

摘要

目前的新冠大流行模型是否应该已经考虑到季节性,这一点还不确定。这是因为当前的环境因素并不能很好地解释这种季节性,尤其是考虑到气候温和的国家之间的气候差异。有一个假设认为,一个主要因素被忽视了:花粉计数。有记录表明花粉会引发强烈的免疫反应,可能会产生一种环境因素,使类似流感的病毒在宿主之外更难存活。这项荷兰研究证实,花粉计数与每周医疗流感咨询量的变化之间存在(高度)显著的负相关,花粉计数与通过处方药物收入衡量的花粉热发病率与每周流感咨询量之间存在高度显著的负相关。这支持了花粉是流感样流行季节性的直接或间接因素的观点。如果在新冠病毒传播期间也观察到季节性,那么花粉很可能发挥了作用。

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PLoS Comput Biol. 2020 May 13;16(5):e1007879. doi: 10.1371/journal.pcbi.1007879. eCollection 2020 May.
2
The Influence of Simulated Sunlight on the Inactivation of Influenza Virus in Aerosols.模拟阳光对气溶胶中流感病毒灭活的影响。
J Infect Dis. 2020 Jan 14;221(3):372-378. doi: 10.1093/infdis/jiz582.
3
Latitudes mediate the association between influenza activity and meteorological factors: A nationwide modelling analysis in 45 Japanese prefectures from 2000 to 2018.
常见花粉调节气道共培养模型中针对类病毒挑战的免疫反应。
J Immunol Res. 2023 Nov 6;2023:6639092. doi: 10.1155/2023/6639092. eCollection 2023.
4
A Review of the Role of Pollen in COVID-19 Infection.花粉在 COVID-19 感染中的作用综述。
Int J Environ Res Public Health. 2023 May 12;20(10):5805. doi: 10.3390/ijerph20105805.
5
Environmental contributions to the interactions of COVID-19 and asthma: A secondary publication and update.环境因素对新型冠状病毒肺炎与哮喘相互作用的影响:二次发表及更新
World Allergy Organ J. 2022 Sep;15(9):100686. doi: 10.1016/j.waojou.2022.100686. Epub 2022 Aug 8.
6
Evaluating COVID-19-Environment Fit.评估 COVID-19-环境适配性。
Acta Biomed. 2022 May 11;93(2):e2022204. doi: 10.23750/abm.v93i2.12161.
7
Environmental factors and mobility predict COVID-19 seasonality in the Netherlands.环境因素和流动性可预测荷兰 COVID-19 的季节性。
Environ Res. 2022 Aug;211:113030. doi: 10.1016/j.envres.2022.113030. Epub 2022 Mar 4.
8
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J Pediatr (Rio J). 2022 Mar-Apr;98 Suppl 1(Suppl 1):S32-S37. doi: 10.1016/j.jped.2021.10.001. Epub 2021 Nov 4.
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Phys Fluids (1994). 2021 Jun;33(6):063313. doi: 10.1063/5.0055845. Epub 2021 Jun 22.
纬度调节流感活动与气象因素之间的关联:2000 年至 2018 年日本 45 个县的全国建模分析。
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J Environ Manage. 2001 Jul;62(3):317-21. doi: 10.1006/jema.2001.0440.