环境对微生物组的影响。
Impact of the environment on the microbiome.
机构信息
Universidade Federal do Paraná, Divisão de Alergia e Imunologia, Curitiba, PR, Brazil.
Federico II University, School of Specialization in Respiratory Diseases, High Specialty Hospital A. Cardarelli, Division of Respiratory and Allergic Diseases, Naples, NA, Italy.
出版信息
J Pediatr (Rio J). 2022 Mar-Apr;98 Suppl 1(Suppl 1):S32-S37. doi: 10.1016/j.jped.2021.10.001. Epub 2021 Nov 4.
OBJECTIVES
This review aimed to verify indoor and outdoor pollution, host and environmental microbiome, and the impact on the health of the pediatric population.
SOURCES
A review of the literature, non-systematic, with the search for articles since 2001 in PubMed with the terms "pollution" AND "microbiome" AND "children's health" AND "COVID-19".
SUMMARY OF THE FINDINGS
Prevention of allergic diseases includes the following aspects: avoid cesarean delivery, the unnecessary overuse of antibiotics, air pollution, smoking in pregnancy and second-hand tobacco smoke, stimulate breastfeeding, soil connection, consume fresh fruits and vegetables, exercise and outdoor activities and animal contact. The children's microbiota richness and diversity decrease the risk of immune disbalance and allergic disease development.
CONCLUSIONS
Lifestyle and exposure to pollutants, both biological and non-biological, modify the host and the environment microbiome provoking an immune disbalance with inflammatory consequences and development of allergic diseases.
目的
本综述旨在验证室内和室外污染、宿主和环境微生物组，以及其对儿科人群健康的影响。
资料来源
对文献进行回顾，非系统性，自 2001 年以来在 PubMed 中使用“污染”和“微生物组”和“儿童健康”和“COVID-19”这两个词进行文章检索。
研究结果概述
预防过敏疾病包括以下方面：避免剖腹产、不必要的抗生素过度使用、空气污染、妊娠期间吸烟和二手烟、刺激母乳喂养、土壤接触、食用新鲜水果和蔬菜、运动和户外活动以及与动物接触。儿童的微生物组丰富度和多样性降低了免疫失衡和过敏疾病发展的风险。
结论
生活方式和暴露于生物和非生物污染物会改变宿主和环境微生物组，引发免疫失衡，并导致炎症后果和过敏疾病的发展。
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