• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Induced Pluripotent Stem Cells (iPSCs) Derived 3D Human Lung Organoids from Different Ethnicities to Understand the SARS-CoV2 Severity/Infectivity Percentage.

作者信息

Bose Bipasha

机构信息

Stem Cells and Regenerative Medicine Centre, Yenepoya Research Centre, Yenepoya (Deemed to be University), University Road, Mangalore, Pincode-575018, Karnataka, India.

出版信息

Stem Cell Rev Rep. 2021 Feb;17(1):293-295. doi: 10.1007/s12015-020-09989-2.

DOI:10.1007/s12015-020-09989-2
PMID:32500482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7272136/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e513/7272136/5ff71a1fdb07/12015_2020_9989_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e513/7272136/5ff71a1fdb07/12015_2020_9989_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e513/7272136/5ff71a1fdb07/12015_2020_9989_Fig1_HTML.jpg

相似文献

1
Induced Pluripotent Stem Cells (iPSCs) Derived 3D Human Lung Organoids from Different Ethnicities to Understand the SARS-CoV2 Severity/Infectivity Percentage.诱导多能干细胞（iPSCs）衍生的来自不同种族的3D人肺类器官，以了解新冠病毒的严重程度/感染率。
Stem Cell Rev Rep. 2021 Feb;17(1):293-295. doi: 10.1007/s12015-020-09989-2.
2
Induced Pluripotent Stem Cell Derived Human Lung Organoids to Map and Treat the SARS-CoV2 Infections In Vitro.诱导多能干细胞衍生的人类肺类器官用于体外绘制和治疗 SARS-CoV2 感染。
Adv Exp Med Biol. 2021;1312:1-17. doi: 10.1007/5584_2020_613.
3
Establishment of Human Pluripotent Stem Cell-Derived Skin Organoids Enabled Pathophysiological Model of SARS-CoV-2 Infection.人多能干细胞衍生皮肤类器官的建立使 SARS-CoV-2 感染的病理生理学模型成为可能。
Adv Sci (Weinh). 2022 Mar;9(7):e2104192. doi: 10.1002/advs.202104192. Epub 2021 Dec 31.
4
Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation.从人类胚胎干细胞和患者特异性诱导多能干细胞生成完整的多细胞类型肺类器官用于传染病建模和治疗验证。
Curr Protoc Stem Cell Biol. 2020 Sep;54(1):e118. doi: 10.1002/cpsc.118.
5
SARS-CoV-2 research using human pluripotent stem cells and organoids.利用人类多能干细胞和类器官进行 SARS-CoV-2 研究。
Stem Cells Transl Med. 2021 Nov;10(11):1491-1499. doi: 10.1002/sctm.21-0183. Epub 2021 Jul 24.
6
Differentiation of human airway-organoids from induced pluripotent stem cells (iPSCs).从诱导多能干细胞（iPSCs）中分化出人类气道类器官。
Methods Cell Biol. 2020;159:95-114. doi: 10.1016/bs.mcb.2020.03.008. Epub 2020 Apr 25.
7
Neurotropic Effects of SARS-CoV-2 Modeled by the Human Brain Organoids.人类脑类器官模拟的 SARS-CoV-2 的神经嗜性。
Stem Cell Reports. 2021 Mar 9;16(3):373-384. doi: 10.1016/j.stemcr.2021.02.007. Epub 2021 Feb 12.
8
Induced Pluripotent Stem Cell-Derived Organoids: Their Implication in COVID-19 Modeling.诱导多能干细胞衍生类器官：它们在新冠病毒疾病建模中的意义
Int J Mol Sci. 2023 Feb 9;24(4):3459. doi: 10.3390/ijms24043459.
9
Induced pluripotent stem cell-based disease modeling and prospective immune therapy for coronavirus disease 2019.基于诱导多能干细胞的 2019 冠状病毒病疾病建模和前瞻性免疫治疗。
Cytotherapy. 2022 Mar;24(3):235-248. doi: 10.1016/j.jcyt.2021.08.003. Epub 2021 Sep 14.
10
Tumor Necrosis Factor-Alpha Exacerbates Viral Entry in SARS-CoV2-Infected iPSC-Derived Cardiomyocytes.肿瘤坏死因子-α加剧 SARS-CoV2 感染的诱导多能干细胞衍生心肌细胞中的病毒进入。
Int J Mol Sci. 2021 Sep 13;22(18):9869. doi: 10.3390/ijms22189869.

引用本文的文献

1
iPSC-derived lung and lung cancer organoid model to evaluate cisplatin encapsulated autologous iPSC-derived mesenchymal stromal cell-isolated extracellular vesicles.用于评估顺铂包裹的自体诱导多能干细胞衍生的间充质基质细胞分离的细胞外囊泡的诱导多能干细胞衍生的肺和肺癌类器官模型
Stem Cell Res Ther. 2024 Aug 7;15(1):246. doi: 10.1186/s13287-024-03862-6.
2
An Insight on Microfluidic Organ-on-a-Chip Models for PM-Induced Pulmonary Complications.对用于颗粒物诱导的肺部并发症的微流控芯片器官模型的见解
ACS Omega. 2024 Mar 7;9(12):13534-13555. doi: 10.1021/acsomega.3c10271. eCollection 2024 Mar 26.
3
Microfluidic strategies for biomimetic lung chip establishment and SARS-CoV2 study.

本文引用的文献

1
SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells.SARS-CoV-2 受体 ACE2 和 TMPRSS2 主要表达于支气管的瞬态分泌细胞中。
EMBO J. 2020 May 18;39(10):e105114. doi: 10.15252/embj.20105114. Epub 2020 Apr 14.
2
Human lung organoids develop into adult airway-like structures directed by physico-chemical biomaterial properties.人类肺类器官在物理化学生物材料特性的引导下发育成类似成人气道的结构。
Biomaterials. 2020 Mar;234:119757. doi: 10.1016/j.biomaterials.2020.119757. Epub 2020 Jan 6.
3
In vitro generation of human pluripotent stem cell derived lung organoids.
用于仿生肺芯片建立和SARS-CoV-2研究的微流控策略
Mater Today Bio. 2023 Dec 7;24:100905. doi: 10.1016/j.mtbio.2023.100905. eCollection 2024 Feb.
4
Harnessing three-dimensional (3D) cell culture models for pulmonary infections: State of the art and future directions.利用三维（3D）细胞培养模型研究肺部感染：现状与未来方向
Naunyn Schmiedebergs Arch Pharmacol. 2023 Nov;396(11):2861-2880. doi: 10.1007/s00210-023-02541-2. Epub 2023 Jun 2.
5
Advanced models for respiratory disease and drug studies.呼吸系统疾病和药物研究的先进模型。
Med Res Rev. 2023 Sep;43(5):1470-1503. doi: 10.1002/med.21956. Epub 2023 Apr 29.
6
3D Human Organoids: The Next "Viral" Model for the Molecular Basis of Infectious Diseases.3D人体类器官：传染病分子基础的下一个“热门”模型。
Biomedicines. 2022 Jun 28;10(7):1541. doi: 10.3390/biomedicines10071541.
7
Two Different Therapeutic Approaches for SARS-CoV-2 in hiPSCs-Derived Lung Organoids.两种不同的治疗方法用于诱导多能干细胞衍生肺类器官中的 SARS-CoV-2。
Cells. 2022 Apr 5;11(7):1235. doi: 10.3390/cells11071235.
8
Role of biomaterials in the diagnosis, prevention, treatment, and study of corona virus disease 2019 (COVID-19).生物材料在2019冠状病毒病（COVID-19）诊断、预防、治疗及研究中的作用
Emergent Mater. 2021;4(1):35-55. doi: 10.1007/s42247-021-00165-x. Epub 2021 Mar 16.
人多能干细胞来源的肺类器官的体外生成。
Elife. 2015 Mar 24;4:e05098. doi: 10.7554/eLife.05098.
4
Toward the development of a global induced pluripotent stem cell library.迈向建立全球诱导多能干细胞库。
Cell Stem Cell. 2013 Oct 3;13(4):382-4. doi: 10.1016/j.stem.2013.08.003.
5
Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation.新兴的新型人类贝塔冠状病毒 2c EMC/2012 对不同细胞系的易感性：对疾病发病机制和临床表现的影响。
J Infect Dis. 2013 Jun 1;207(11):1743-52. doi: 10.1093/infdis/jit123. Epub 2013 Mar 26.