Windsor J A, Hill G L
Department of Surgery, University of Auckland School of Medicine, New Zealand.
Aust N Z J Surg. 1988 Sep;58(9):711-5. doi: 10.1111/j.1445-2197.1988.tb01101.x.
This study was designed to test the hypothesis that protein depleted surgical patients are at an increased risk of postoperative complications following major surgery; 101 patients and 59 normal volunteers had measurements of nutritional status (weight loss (%), midarm muscle circumference, plasma transferrin and prealbumin concentration and a direct measurement of pre-operative protein depletion, the protein index) and the patient's postoperative course was carefully monitored from the time of operation until discharge. The patients were divided into two categories on the basis of the extent of protein depletion: non-protein depleted patients (4% mean protein loss) and protein depleted patients (39% mean protein loss). The protein depleted patients had a significantly higher incidence of major complications, pneumonia and stayed in hospital longer (both overall stay and postoperatively).
蛋白质缺乏的外科手术患者在接受大手术后发生术后并发症的风险会增加；对101例患者和59名正常志愿者进行了营养状况测量（体重减轻百分比、上臂中部肌肉周长、血浆转铁蛋白和前白蛋白浓度以及术前蛋白质缺乏的直接测量指标——蛋白质指数），并从手术时起直至出院对患者的术后病程进行了仔细监测。根据蛋白质缺乏程度将患者分为两类：非蛋白质缺乏患者（平均蛋白质损失4%）和蛋白质缺乏患者（平均蛋白质损失39%）。蛋白质缺乏患者发生严重并发症、肺炎的发生率显著更高，住院时间更长（包括总住院时间和术后住院时间）。
