Higgens C S, Keighley M R, Allan R N
Gut. 1984 Jul;25(7):732-6. doi: 10.1136/gut.25.7.732.
One hundred and twenty seven patients undergoing elective surgery for inflammatory bowel disease were divided into three groups according to their preoperative ideal body weight (less than 80%, 80-90%, and greater than 90%). The groups were well matched in respect of age, sex, corticosteroid therapy, pre-existing sepsis, peroperative antimicrobial chemotherapy, and resection site. None received peroperative nutritional support. The postoperative outcome was similar in each of the three nutritional groups including the incidence of postoperative sepsis, duration of hospital stay, and mortality. Serial peroperative changes in weight, fat, and muscle bulk were assessed by anthropometric measurements in 21 of these patients. The deficits in weight, fat, and muscle bulk were similar at 10 and 21 days postoperatively in the three groups. At 84 days those malnourished preoperatively had recovered their nutritional status faster than the well nourished patients. We conclude that in these patients undergoing elective resection for inflammatory bowel disease preoperative weight loss did not adversely affect the postoperative outcome.
127例接受择期手术治疗炎症性肠病的患者，根据其术前理想体重分为三组（低于80%、80 - 90%、高于90%）。三组在年龄、性别、皮质类固醇治疗、既往败血症、围手术期抗菌化疗及切除部位方面匹配良好。均未接受围手术期营养支持。三个营养组的术后结局相似，包括术后败血症发生率、住院时间及死亡率。对其中21例患者通过人体测量评估围手术期体重、脂肪及肌肉量的连续变化。三组术后10天和21天体重、脂肪及肌肉量的缺失相似。在84天时，术前营养不良的患者比营养良好的患者营养状况恢复得更快。我们得出结论，在这些接受择期手术切除炎症性肠病的患者中，术前体重减轻并未对术后结局产生不利影响。
