儿童患者牙龈骨化性肌纤维母细胞瘤：免疫组织化学分析及文献复习。

Gingival ossifying myopericytoma in a pediatric patient: Immunohistochemical analysis and literature review.

机构信息

Department of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café S/N, 14040-904 Ribeirão Preto, SP, Brazil.

Oral Pathology, Department of Stomatology, Public Oral Health, and Forensic Dentistry, Ribeirão Preto Dental School (FORP/USP), University of São Paulo, Avenida do Café S/N, 14040-904 Ribeirão Preto, SP, Brazil.

出版信息

Oral Oncol. 2020 Aug;107:104826. doi: 10.1016/j.oraloncology.2020.104826. Epub 2020 Jun 4.

DOI:10.1016/j.oraloncology.2020.104826

PMID:32505552

Abstract

Myopericytoma is a rare mesenchymal tumor characterized by a hemangiopericytoma-like vascular pattern with perivascular myoid differentiation. To date, only 11 cases of oral myopericytoma have been reported. To the best of our knowledge, myopericytoma with gingival involvement and associated with calcifications has not been reported, expanding their clinicopathological spectrum. Herein, we report a 12-year-old girl female patient who presented a gingival nodule diagnosed as ossifying myopericytoma, which should be considered in the differential diagnosis when assessing oral soft tissue lesions, especially in pediatric patients.

摘要

肌纤维母细胞瘤是一种罕见的间叶性肿瘤，其特征为具有血管外皮细胞瘤样血管模式和血管周肌样分化。迄今为止，仅报道了 11 例口腔肌纤维母细胞瘤。据我们所知，尚无牙龈受累并伴有钙化的肌纤维母细胞瘤的报道，这扩大了其临床病理谱。本文报告了 1 例 12 岁女性患者，其表现为牙龈结节，诊断为骨化性肌纤维母细胞瘤，在评估口腔软组织病变时，尤其是在儿科患者中，应考虑将其作为鉴别诊断。