Department of Gastroenterology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan 430014, China.
Department of Gastroenterology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan 430014, China.
Dig Liver Dis. 2020 Oct;52(10):1076-1079. doi: 10.1016/j.dld.2020.04.034. Epub 2020 May 8.
To explore the clinical characteristics of Coronavirus Disease (COVID-19) patients with gastrointestinal symptoms.
The clinical data of 164 COVID-19 patients with gastrointestinal symptoms were extracted and analysed retrospectively.
In total, 505 COVID-19 patients were divided into two groups: those with gastrointestinal symptoms (G group) and those without gastrointestinal symptoms (NG group). Common gastrointestinal symptoms included inappetence, diarrhoea, nausea, abdominal pain, and vomiting. Significantly higher proportions of patients with fever, dizziness, myalgia, and fatigue were noted in group G than in group NG. Compared with patients without fever, there was a significant difference between G group and NG group in moderate fever or above, while there was no significant difference between the two groups in low fever. The laboratory results showed that patients in the G group had significantly higher C-reactive protein, lactate dehydrogenase, and α-hydroxybutyrate dehydrogenase levels than those in the NG group. Moreover, the proportion of patients with severe pneumonia was significantly higher in the G group than in the NG group.
In Wuhan, the proportion of COVID-19 patients who experience gastrointestinal symptoms is relatively high. Patients who experience gastrointestinal symptoms are more likely to suffer from severe pneumonia, which may help clinicians identify patients at high risk of COVID-19 and thus reduce the incidence of this condition.
探讨以胃肠道症状为主要表现的新型冠状病毒肺炎（COVID-19）患者的临床特征。
回顾性提取并分析了 164 例以胃肠道症状为主要表现的 COVID-19 患者的临床资料。
共纳入 505 例 COVID-19 患者，分为合并胃肠道症状组（G 组）和无胃肠道症状组（NG 组）。常见的胃肠道症状包括食欲不振、腹泻、恶心、腹痛和呕吐。G 组患者发热、头晕、肌痛和乏力的比例明显高于 NG 组。与无发热患者相比，G 组中度及以上发热患者与 NG 组相比差异有统计学意义，而两组低热患者差异无统计学意义。实验室结果显示，G 组患者 C 反应蛋白、乳酸脱氢酶和 α-羟丁酸脱氢酶水平明显高于 NG 组。此外，G 组患者重症肺炎的比例明显高于 NG 组。
在武汉，以胃肠道症状为主要表现的 COVID-19 患者比例相对较高。出现胃肠道症状的患者更易发生重症肺炎，这可能有助于临床医生识别 COVID-19 高危患者，从而降低该疾病的发生率。
