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更年期症状与更年期类型及血脂水平的关系。

The relationship of menopausal symptoms with the type of menopause and lipid levels.

作者信息

Demir Omer, Ozalp Mirac, Sal Hidayet, Aran Turhan, Osmanağaoğlu Mehmet A

机构信息

Department of Gynecology and Obstetrics, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey.

出版信息

Prz Menopauzalny. 2020 Mar;19(1):6-10. doi: 10.5114/pm.2020.95300. Epub 2020 Apr 27.

Abstract

INTRODUCTION

Many postmenopausal women experience hot flashes, night sweats, decreased sexual desire and vaginal dryness. In this study, we aimed to compare the menopause symptom levels of surgical menopause patients and natural menopause patients by using a Menopause Rating Scale (MRS) and investigate whether there is a relationship between lipid levels and menopausal symptoms in surgical menopause patients.

MATERIAL AND METHODS

This cross-sectional study was conducted on postmenopausal women who applied to the gynecology outpatient clinic. A total of 187 patients were analyzed. Of these,112 were the surgical menopause group and the remaining 75 were the natural menopause group. Total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides were measured by using an enzymatic color test. In order to evaluate the postmenopausal symptoms of postmenopausal women included in the study, the MRS questionnaire adapted to the Turkish population was used.

RESULTS

Considering the results of the MRS of the two groups, the results of surgical menopause patients were found to be statistically significantly higher. The results were statistically significantly higher in both the total score and in the two subgroups(somatic and psychological subgroups)in the surgical menopause group. When the MRS results(subgroups and total score)of women in the surgical menopause group were classified as mild and severe, no statistically significant relationship was found between symptom severity and blood lipid levels.

CONCLUSIONS

In the surgically induced menopause group, it was shown by this study that menopausal symptoms were more severe than the natural menopause group. Unlike natural menopausal patients, no relationship was found between lipid levels and severity of menopausal symptoms in surgical menopausal patients.

摘要

引言

许多绝经后女性会经历潮热、盗汗、性欲减退和阴道干燥。在本研究中,我们旨在使用绝经评定量表(MRS)比较手术绝经患者和自然绝经患者的绝经症状水平,并调查手术绝经患者的血脂水平与绝经症状之间是否存在关联。

材料与方法

本横断面研究针对申请到妇科门诊就诊的绝经后女性进行。共分析了187例患者。其中,112例为手术绝经组,其余75例为自然绝经组。采用酶比色法测量总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇和甘油三酯。为评估纳入研究的绝经后女性的绝经症状,使用了适用于土耳其人群的MRS问卷。

结果

考虑到两组的MRS结果,发现手术绝经患者的结果在统计学上显著更高。手术绝经组的总分以及两个亚组(躯体和心理亚组)的结果在统计学上均显著更高。将手术绝经组女性的MRS结果(亚组和总分)分为轻度和重度时,未发现症状严重程度与血脂水平之间存在统计学上的显著关系。

结论

本研究表明,在手术诱导绝经组中,绝经症状比自然绝经组更严重。与自然绝经患者不同,手术绝经患者的血脂水平与绝经症状严重程度之间未发现关联。

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