Jiang Lingling, Lin Juan, Yan Jianying, Lin Xiaoqian, Han Qing, Zhang Huale
Department of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350000, P.R. China.
Exp Ther Med. 2020 Jul;20(1):500-504. doi: 10.3892/etm.2020.8677. Epub 2020 Apr 22.
The present study aimed to determine the clinical characteristics and perinatal outcomes of females with severe preeclampsia according to their pre-pregnancy body mass index (BMI). Data from 233 patients with severe preeclampsia were reviewed from the Inpatient Obstetrics Department. The data were divided into 3 groups according to the patients' pre-pregnancy BMI: Normal (BMI of 18-25 kg/m; n=134); underweight (BMI <18 kg/m; n=15); and overweight and obese (BMI >25 kg/m; n=84). The incidence of dyslipidemia, amniotic fluid abnormalities and neonatal hospitalizations in the group of females who were overweight or obese before pregnancy were higher than those in the other groups (all P<0.05). In conclusion, the presence of dyslipidemia, excessive weight and obesity prior to pregnancy in patients with severe preeclampsia was associated with maternal and perinatal outcomes.
本研究旨在根据孕前体重指数(BMI)确定重度子痫前期女性的临床特征和围产期结局。回顾了住院产科233例重度子痫前期患者的数据。根据患者孕前BMI将数据分为3组:正常组(BMI为18 - 25 kg/m²;n = 134);体重过轻组(BMI < 18 kg/m²;n = 15);超重和肥胖组(BMI > 25 kg/m²;n = 84)。孕前超重或肥胖女性组的血脂异常、羊水异常和新生儿住院发生率高于其他组(均P < 0.05)。总之,重度子痫前期患者孕前存在血脂异常、体重过重和肥胖与母婴围产期结局相关。