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孕前体重指数与子痫前期女性的围产期结局相关。

Prepregnancy body mass indexes are associated with perinatal outcomes in females with preeclampsia.

作者信息

Jiang Lingling, Lin Juan, Yan Jianying, Lin Xiaoqian, Han Qing, Zhang Huale

机构信息

Department of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350000, P.R. China.

出版信息

Exp Ther Med. 2020 Jul;20(1):500-504. doi: 10.3892/etm.2020.8677. Epub 2020 Apr 22.

Abstract

The present study aimed to determine the clinical characteristics and perinatal outcomes of females with severe preeclampsia according to their pre-pregnancy body mass index (BMI). Data from 233 patients with severe preeclampsia were reviewed from the Inpatient Obstetrics Department. The data were divided into 3 groups according to the patients' pre-pregnancy BMI: Normal (BMI of 18-25 kg/m; n=134); underweight (BMI <18 kg/m; n=15); and overweight and obese (BMI >25 kg/m; n=84). The incidence of dyslipidemia, amniotic fluid abnormalities and neonatal hospitalizations in the group of females who were overweight or obese before pregnancy were higher than those in the other groups (all P<0.05). In conclusion, the presence of dyslipidemia, excessive weight and obesity prior to pregnancy in patients with severe preeclampsia was associated with maternal and perinatal outcomes.

摘要

本研究旨在根据孕前体重指数(BMI)确定重度子痫前期女性的临床特征和围产期结局。回顾了住院产科233例重度子痫前期患者的数据。根据患者孕前BMI将数据分为3组:正常组(BMI为18 - 25 kg/m²;n = 134);体重过轻组(BMI < 18 kg/m²;n = 15);超重和肥胖组(BMI > 25 kg/m²;n = 84)。孕前超重或肥胖女性组的血脂异常、羊水异常和新生儿住院发生率高于其他组(均P < 0.05)。总之,重度子痫前期患者孕前存在血脂异常、体重过重和肥胖与母婴围产期结局相关。

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本文引用的文献

1
Preeclampsia: Pathophysiology, Challenges, and Perspectives.子痫前期:病理生理学、挑战与展望。
Circ Res. 2019 Mar 29;124(7):1094-1112. doi: 10.1161/CIRCRESAHA.118.313276.
2
Serum lipids and risk of obesity-related cancers in postmenopausal women.绝经后女性的血清脂质与肥胖相关癌症风险
Cancer Causes Control. 2018 Jan;29(1):13-24. doi: 10.1007/s10552-017-0991-y. Epub 2017 Dec 2.
10
Effects of maternal obesity on antenatal, perinatal and neonatal outcomes.母亲肥胖对产前、围产期及新生儿结局的影响。
J Matern Fetal Neonatal Med. 2015;28(17):2080-3. doi: 10.3109/14767058.2014.978279. Epub 2014 Nov 11.

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