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急诊科收治的农药中毒患者的概况与转归

Profile and outcome of patients presenting with agrochemical poisoning to the emergency department.

作者信息

Sivanandan A, Abel S R, Sanjay M, Chandran Jolly, Gunasekaran Karthik, Abhilash Kundavaram Paul Prabhakar

机构信息

Department of Emergency Medicine, Christian Medical College, Vellore, Tamil Nadu, India.

Department of Emergency Medicine, Accident and Emergency Care Technology, Paramedic, Department of Emergency Medicine, Christian Medical College, Vellore, Tamil Nadu, India.

出版信息

J Family Med Prim Care. 2020 Mar 26;9(3):1589-1593. doi: 10.4103/jfmpc.jfmpc_1096_19. eCollection 2020 Mar.

Abstract

BACKGROUND

Deliberate self-harm (DSH) is one of the leading causes of mortality and morbidity in India. Agrochemicals are the most commonly used compounds for DSH. The spectrum of Agrochemicals in use varies from region to region and time period with newer compound being regularly introduced into the market.

METHODOLOGY

This retrospective cohort study included patients presenting with agrochemical poisoning to the ED during January 2017 to December 2018. Patient data was retrieved form the ED triage registry software and clinical workstation, following which their hospital outcome was determined.

RESULTS

During the study period, 1802 patients presented with DSH among which Agrochemical poisoning comprised 33.5% (604/1802). The mean age was 31 years and incidence of agrochemical poisoning was found to be higher in young adults (16-30 years-55.8%). The prevalence was more common in males (62.4%). The common agrochemical compounds consumed were insecticides (91%), herbicides (4.3%), fungicides (1.5%), fertilizer (1.5%), and plant growth regulators (1.5%). Majority (80.96%) of the patients were discharged alive from the hospital, 17% left against medical advice due to bad prognosis and 12 patients (2%) died in the hospital.

CONCLUSION

Insecticides (mainly Organophosphates) are the most common agrochemicals used for DSH. Their management is better understood leading to better outcomes compared to other chemicals. The proportion of agrochemical use in DSH has reduced over the last decade. Imidacloprid (Insecticide) and Plant growth regulators are the new compounds for which appropriate management is not yet established and more research is needed.

摘要

背景

蓄意自伤(DSH)是印度死亡率和发病率的主要原因之一。农用化学品是DSH最常用的化合物。不同地区和时间段使用的农用化学品种类各不相同,新化合物也在不断推向市场。

方法

这项回顾性队列研究纳入了2017年1月至2018年12月期间因农用化学品中毒到急诊科就诊的患者。从急诊科分诊登记软件和临床工作站检索患者数据,随后确定他们的医院结局。

结果

在研究期间,1802例患者出现DSH,其中农用化学品中毒占33.5%(604/1802)。平均年龄为31岁,发现农用化学品中毒在年轻人(16 - 30岁,占55.8%)中发病率更高。患病率在男性中更常见(62.4%)。使用的常见农用化学品化合物有杀虫剂(91%)、除草剂(4.3%)、杀菌剂(1.5%)、肥料(1.5%)和植物生长调节剂(1.5%)。大多数(80.96%)患者从医院存活出院,17%因预后不良自动出院,12例患者(2%)在医院死亡。

结论

杀虫剂(主要是有机磷)是用于DSH最常见的农用化学品。与其他化学品相比,对其管理有更好的理解,从而带来更好的结局。在过去十年中,DSH中农用化学品的使用比例有所下降。吡虫啉(杀虫剂)和植物生长调节剂是新的化合物,尚未建立适当的管理方法,需要更多研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fda/7266212/a39810219e7f/JFMPC-9-1589-g001.jpg

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