Abdelazim Ibrahim A, Bekmukhambetov Yerbol, Aringazina Raisa, Shikanova Svetlana, Amer Osama O, Zhurabekova Gulmira, Otessin Makhmutsultangali A, Astrakhanov Akezhan R
Department of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt.
Department of Obstetrics and Gynecology, Ahmadi Hospital, Kuwait Oil Company, Ahmadi, Kuwait.
J Family Med Prim Care. 2020 Mar 26;9(3):1678-1683. doi: 10.4103/jfmpc.jfmpc_1054_19. eCollection 2020 Mar.
Hypertensive disorders (HTDs) with pregnancy remain a major health problem because of the associated adverse maternal and perinatal adverse outcomes.
To evaluate the outcomes of HTDs with pregnancy.
Four hundred and five (405) hypertensive women included in this retrospective multicenter study. Data of the studied women including maternal age, parity, gestational age at delivery, pregnancy outcome [preterm delivery (PTD), birth weight (LBW), Apgar scores, neonatal intensive care unit admission (NICU), intrauterine fetal death (IUFD), intrapartum and/or early neonatal deaths] were collected. Collected data analyzed statistically to evaluate the outcome of HTDs with pregnancy.
Preeclampsia (PE)/superimposed PE group had significantly high relative risk (RR) and Odds ratio (OR) for PTD (RR 2.1; OR; 3.3; = 0.0001 and = 0.0001, respectively), LBW (RR 2.01; OR; 3.17; = 0.0001 and = 0.0001, respectively), and low Apgar score at 1 min (RR 1.7; OR 1.9; = 0.01 and 0.01, respectively) and at 5 min (RR 2.2; OR; 2.36; = 0.2 and 0.2; respectively). In addition, PE/superimposed PE group had significantly high RR and OR for NICU admission (RR 1.6; OR 2.2; < 0.0002 and < 0.0001, respectively) and IUFD (RR 2.9; OR 3.1; = 0.01 and 0.01, respectively).
women with PE/superimposed PE have high RR and OR for PTD, LBW, and low Apgar score at 1 and 5 min, NICU, and IUFD compared to the gestational and chronic hypertension with pregnancy.
妊娠高血压疾病（HTDs）由于其相关的孕产妇和围产期不良结局，仍然是一个主要的健康问题。
评估妊娠高血压疾病的结局。
本回顾性多中心研究纳入了405名高血压女性。收集了研究对象的相关数据，包括产妇年龄、产次、分娩时的孕周、妊娠结局[早产（PTD）、低出生体重（LBW）、阿氏评分、新生儿重症监护病房收治情况（NICU）、宫内胎儿死亡（IUFD）、产时和/或早期新生儿死亡]。对收集到的数据进行统计学分析，以评估妊娠高血压疾病的结局。
子痫前期（PE）/叠加子痫前期组发生早产（PTD）的相对风险（RR）和比值比（OR）显著升高（RR分别为2.1；OR分别为3.3；P值均为0.0001），低出生体重（LBW）的RR（2.01）和OR（3.17）也显著升高（P值均为0.0001），1分钟时低阿氏评分的RR（1.7）和OR（1.9）显著升高（P值分别为0.01和0.01），5分钟时RR（2.2）和OR（2.36）也显著升高（P值分别为0.2和0.2）。此外，PE/叠加子痫前期组入住新生儿重症监护病房（NICU）的RR（1.6）和OR（2.2）显著升高（P值分别<0.0002和<0.0001），宫内胎儿死亡（IUFD）的RR（2.9）和OR（3.1）显著升高（P值均为0.01）。
与妊娠期高血压和慢性高血压合并妊娠相比，患有PE/叠加子痫前期的女性发生早产、低出生体重、1分钟和5分钟时低阿氏评分、入住新生儿重症监护病房以及宫内胎儿死亡的RR和OR更高。
