Suppr超能文献

接受精神科治疗的成年人中苯二氮䓬类药物的滥用情况。

Benzodiazepine misuse among adults receiving psychiatric treatment.

作者信息

McHugh R Kathryn, Peckham Andrew D, Björgvinsson Thröstur, Korte Francesca M, Beard Courtney

机构信息

McLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck St., Boston, MA, 02115, USA.

McLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck St., Boston, MA, 02115, USA.

出版信息

J Psychiatr Res. 2020 Sep;128:33-37. doi: 10.1016/j.jpsychires.2020.05.020. Epub 2020 May 24.

Abstract

Benzodiazepines are among the most commonly prescribed psychiatric medications and have the potential for misuse. People with psychiatric disorders may have a heightened liability to the reinforcing effects of benzodiazepines. Yet, the prevalence of benzodiazepine misuse in psychiatric care settings is not well characterized. The aim of the current study was to characterize the prevalence and correlates of benzodiazepine misuse in a sample of adults receiving psychiatric treatment (N = 589). The majority of participants reported a lifetime history of benzodiazepine prescription (68%) and 26% reported a lifetime history of misuse (defined as use without a prescription or at a dose or frequency higher than prescribed). Multivariable analyses indicated that history of a benzodiazepine prescription and drug use problems were significantly associated with lifetime benzodiazepine misuse. People with a history of benzodiazepine prescription had four times higher odds of misusing benzodiazepines and the primary source of misused benzodiazepines was from family or friends. Results suggest that benzodiazepine misuse is not exclusive to substance use disorder populations. The misuse of benzodiazepines should be assessed in psychiatric settings. Further research is needed to understand the impact of benzodiazepine misuse in this population and to develop tools to identify those at risk for misuse.

摘要

苯二氮䓬类药物是最常被处方的精神科药物之一,存在被滥用的可能性。患有精神疾病的人可能对苯二氮䓬类药物的强化作用更易产生依赖。然而,在精神科护理环境中苯二氮䓬类药物滥用的患病率尚未得到充分描述。本研究的目的是描述在接受精神科治疗的成年样本(N = 589)中苯二氮䓬类药物滥用的患病率及其相关因素。大多数参与者报告有苯二氮䓬类药物的终生处方史(68%),26%报告有终生滥用史(定义为无处方使用或使用剂量或频率高于规定)。多变量分析表明,苯二氮䓬类药物处方史和药物使用问题与终生苯二氮䓬类药物滥用显著相关。有苯二氮䓬类药物处方史的人滥用苯二氮䓬类药物的几率高出四倍,滥用的苯二氮䓬类药物的主要来源是家人或朋友。结果表明,苯二氮䓬类药物滥用并非仅见于物质使用障碍人群。在精神科环境中应评估苯二氮䓬类药物的滥用情况。需要进一步研究以了解苯二氮䓬类药物滥用对该人群的影响,并开发工具来识别有滥用风险的人群。

相似文献

5
The epidemiology of benzodiazepine misuse: A systematic review.苯二氮䓬类药物滥用的流行病学:系统评价。
Drug Alcohol Depend. 2019 Jul 1;200:95-114. doi: 10.1016/j.drugalcdep.2019.02.033. Epub 2019 May 7.

引用本文的文献

本文引用的文献

1
The epidemiology of benzodiazepine misuse: A systematic review.苯二氮䓬类药物滥用的流行病学:系统评价。
Drug Alcohol Depend. 2019 Jul 1;200:95-114. doi: 10.1016/j.drugalcdep.2019.02.033. Epub 2019 May 7.
2
Patterns in Outpatient Benzodiazepine Prescribing in the United States.美国门诊苯二氮䓬类药物处方模式。
JAMA Netw Open. 2019 Jan 4;2(1):e187399. doi: 10.1001/jamanetworkopen.2018.7399.
8
Validation of the PHQ-9 in a psychiatric sample.PHQ-9在一个精神科样本中的效度验证。
J Affect Disord. 2016 Mar 15;193:267-73. doi: 10.1016/j.jad.2015.12.075. Epub 2015 Dec 31.
10
Benzodiazepine use in the United States.苯二氮䓬类药物在美国的使用情况。
JAMA Psychiatry. 2015 Feb;72(2):136-42. doi: 10.1001/jamapsychiatry.2014.1763.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验