Instituto de Investigación en Salud y Desarrollo (IINSAD), cátedra de Parasitología, Facultad de Medicina, Universidad Mayor de San Andrés (UMSA), La Paz, Bolivia.
Centro Municipal de Faeno, Gobierno Autónomo Municipal de La Paz, La Paz, Bolivia.
Parasitology. 2020 Aug;147(9):949-956. doi: 10.1017/S0031182020000529. Epub 2020 Apr 1.
Cystic echinococcosis (CE) is a zoonotic disease caused by a complex of species known as Echinococcus granulosus sensu lato. CE is endemic in Argentina, Chile, Peru, Uruguay and the South part of Brazil. In contrast, little is known regarding the presence of CE in Bolivia. In this study, 35 cysts isolated from livestock (mostly from the Department of La Paz) and 3 from humans (La Paz, Oruro and Potosi) were genetically characterized analysing the sequence of the cox1 gene (1609 bp). In total, 30 cysts (from La Paz, Cochabamba and Beni) were characterized as E. granulosus sensu stricto (3 fertile and 4 non-fertile cysts from sheep, 8 fertile and 12 non-fertile cysts from cattle and 3 fertile cysts from humans). A detailed analysis of the cox1 haplotypes of E. granulosus s.s. is included. Echinococcus ortleppi (G5) was found in 5 fertile cysts from cattle (from La Paz and Cochabamba). Echinococcus intermedius (G7) was identified in 3 fertile cysts from pigs (from Santa Cruz). Additionally, E. granulosus s.s. was detected in 4 dog faecal samples, while E. ortleppi was present in other two dog faecal samples. The implications of these preliminary results in the future implementation of control measures are discussed.
包虫病（CE）是一种由细粒棘球绦虫复合体引起的人畜共患疾病。CE 在阿根廷、智利、秘鲁、乌拉圭和巴西南部流行。相比之下，玻利维亚的 CE 流行情况知之甚少。在这项研究中，从家畜（主要来自拉巴斯省）中分离出 35 个囊肿和 3 个人体囊肿（均来自拉巴斯、奥鲁罗和波托西），并通过分析 cox1 基因序列（1609bp）对其进行了基因特征分析。总共 30 个囊肿（来自拉巴斯、科恰班巴和贝尼）被鉴定为细粒棘球绦虫（3 个绵羊的有生殖能力和 4 个无生殖能力的囊肿、8 个牛的有生殖能力和 12 个无生殖能力的囊肿和 3 个人的有生殖能力的囊肿）。详细分析了细粒棘球绦虫的 cox1 单倍型。在来自拉巴斯和科恰班巴的 5 个牛的有生殖能力的囊肿中发现了细粒棘球蚴（G5）。在来自圣克鲁斯的 3 个猪的有生殖能力的囊肿中鉴定出了中间棘球绦虫（G7）。此外，在 4 个狗粪便样本中检测到了细粒棘球绦虫，而在另外 2 个狗粪便样本中存在细粒棘球蚴。讨论了这些初步结果对未来实施控制措施的影响。
