Hamley I W
Centre for Self-Organising Molecular Systems, University of Leeds, Leeds, LS2 9JT, UK.
Soft Matter. 2005 May 27;1(1):36-43. doi: 10.1039/b418226j.
Recent work exploring the use of block copolymer vesicles and tubules is reviewed. The stability and toughness of block copolymer vesicles are enhanced compared to those formed by low molar mass amphiphiles. Functionality can also readily be introduced through the polymer chemistry or by incorporating additional components (for example pore-forming membrane proteins). This design flexibility leads to numerous potential applications in encapsulation, in targeted drug delivery, templating of inorganic materials and many others.
本文综述了近期关于嵌段共聚物囊泡和微管应用的研究工作。与低摩尔质量两亲分子形成的囊泡相比,嵌段共聚物囊泡的稳定性和韧性有所增强。通过聚合物化学方法或引入其他成分(如成孔膜蛋白),也能够轻松实现功能化。这种设计灵活性为其在封装、靶向给药、无机材料模板制备等众多领域带来了潜在应用。