西班牙西北部新冠疫情对缺血性脑卒中入院和住院死亡率的影响。
Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain.
机构信息
Stroke Unit, Department of Neurology, 16488Hospital Universitario Miguel Servet, Zaragoza, Spain.
Interventional Neuroradiology Unit, Department of Radiology, 16488Hospital Universitario Miguel Servet, Zaragoza, Spain.
出版信息
Int J Stroke. 2020 Oct;15(7):755-762. doi: 10.1177/1747493020938301. Epub 2020 Jun 26.
BACKGROUND AND PURPOSE
Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital stroke admissions and in-hospital mortality in tertiary referral hospitals from North-West Spain.
METHODS
Spanish multicenter retrospective observational study based on data from tertiary hospitals of the NORDICTUS network. We recorded the number of patients admitted for ischemic stroke between 30 December 2019 and 3 May 2020, the number of IVT and EVT procedures, and in-hospital mortality.
RESULTS
In the study period, 2737 patients were admitted with ischemic stroke. There was a decrease in the weekly mean admitted patients during the pandemic (124 vs. 173, p<0.001). In-hospital mortality of stroke patients increased significantly (9.9% vs. 6.5%, p = 0.003), but there were no differences in the proportion of IVT (17.3% vs. 16.1%, p = 0.405) or EVT (22% vs. 23%, p = 0.504).
CONCLUSION
We found a decrease in the number of ischemic stroke admissions and an increase in in-hospital mortality during the COVID-19 epidemic in this large study from North-West Spain. There were regional changes within the network, not fully explained by the severity of the pandemic in different regions.
背景与目的
西班牙是受 COVID-19 影响严重的国家之一。但这场疫情并非对所有地区造成同等影响。我们分析了 COVID-19 大流行对西班牙西北部三级转诊医院的卒中住院人数和院内死亡率的影响。
方法
这是一项基于 NORDICTUS 网络的三级医院数据的西班牙多中心回顾性观察性研究。我们记录了 2019 年 12 月 30 日至 2020 年 5 月 3 日期间因缺血性卒中入院的患者人数、IVT 和 EVT 手术数量以及院内死亡率。
结果
在研究期间，有 2737 例患者因缺血性卒中入院。大流行期间每周平均入院患者数减少（124 例 vs. 173 例，p<0.001）。卒中患者的院内死亡率显著升高（9.9% vs. 6.5%，p=0.003），但 IVT 比例（17.3% vs. 16.1%，p=0.405）或 EVT 比例（22% vs. 23%，p=0.504）无差异。
结论
在这项来自西班牙西北部的大型研究中，我们发现 COVID-19 大流行期间缺血性卒中入院人数减少，院内死亡率升高。网络内存在区域性变化，无法完全用不同地区疫情严重程度来解释。
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