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气腔播散（STAS）在肺腺癌预后及治疗决策中的作用

The role of spread through air spaces (STAS) in lung adenocarcinoma prognosis and therapeutic decision making.

作者信息

Toki Maria I, Harrington Kevin, Syrigos Konstantinos N

机构信息

Yale University School of Medicine, Department of Pathology, New Haven, United States; National and Kapodistrian University of Athens, Greece.

The Institute of Cancer Research/The Royal Marsden, London, United Kingdom.

出版信息

Lung Cancer. 2020 Aug;146:127-133. doi: 10.1016/j.lungcan.2020.04.026. Epub 2020 May 12.

DOI:10.1016/j.lungcan.2020.04.026
PMID:32534331
Abstract

Spread through air spaces (STAS) was included as a novel pattern of invasion in lung adenocarcinoma by the World Health Organization in 2015. Since then, multiple studies have investigated the association of STAS with clinicopathological and molecular features and its implication in the prognosis of early stage lung cancer patients undergoing different surgery types. The aim of this comprehensive review is to present current data on the role of STAS and its perspective in lung adenocarcinoma management.

摘要

气腔播散（STAS）在2015年被世界卫生组织列为肺腺癌一种新的侵袭模式。自那时起，多项研究探讨了STAS与临床病理及分子特征的关联，以及其在接受不同手术类型的早期肺癌患者预后中的意义。这篇综述的目的是展示关于STAS在肺腺癌治疗中的作用及前景的当前数据。

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