Department of Animal and Poultry Production Faculty of Agriculture and Natural Resources, Aswan University, Aswan, Egypt.
Department of Animal Production, Faculty of Agriculture, Cairo University, Giza, Egypt.
Trop Anim Health Prod. 2020 Nov;52(6):2969-2976. doi: 10.1007/s11250-020-02314-6. Epub 2020 Jun 14.
The current investigation aims to evaluate the effects of flunixin meglumine (FM) and aspirin as non-steroid anti-inflammatory drug (NSAID) administration on estrous cycles characteristics and conception rate of Egyptian Baladi cows during hot season. In the first phase, 30 cows were divided into 3 groups, 10 cows for each treatment. The first group was treated with FM at the rate of 1.1 mg/kg body weight (BW) intramuscular, while the second group was administrated aspirin solution orally at the rate of 50 mg/kg BW. The third group was assigned as control (CG) that has no treatment. The FM group was administrated on day 14 after mating, while aspirin was given on day 14 and day 15 post-mating. All cows were mated naturally after showing estrus signs. Pregnancy diagnosis was carried 60 days after mating by rectal palpation. In the second phase, cows were monitored for estrus behavior by visual observation twice a day. The length of normal estrous cycles was 20, 23, and 22 days in cows treated with FM, aspirin, and control cows, respectively. There was no significant effect of treatment on the length of normal estrous cycles in Egyptian cows (P < 0.05). Proportions of long cycles in Egyptian cows that treated with FM or aspirin and control were 75, 67.7, and 57.1%, respectively. Short cycles were completely absent in cows that treated with FM or aspirin, but it was 29% in CG. Mounting behavior and tail rising were not detected in CG compared to 0 and 33% in FM or 25 and 33% in aspirin treated cows, respectively. Conception or pregnancy rate were 60, 40, and 30%, respectively, in FM, aspirin treated, and CG. Treatment cows whether FM or aspirin group did not influence (P < 0.05) progesterone concentration during the 14 days and 21 days from estrous cycle in pregnant and non-pregnant Egyptian Baladi cows than CG. In conclusion, the results of this study clearly indicated beneficial effect of FM and aspirin administration on intense of displayed estrous behavior and conception rate of Egyptian Baladi cows during the hot season.
本研究旨在评估氟尼辛甲胺（FM）和阿司匹林作为非甾体抗炎药（NSAID）在热季对埃及巴尔迪奶牛发情周期特征和受孕率的影响。在第一阶段，将 30 头奶牛分为 3 组，每组 10 头。第一组肌肉注射 FM，剂量为 1.1mg/kg 体重（BW）；第二组口服阿司匹林溶液，剂量为 50mg/kg BW。第三组为对照组（CG），不进行任何治疗。FM 组在配种后第 14 天给药，阿司匹林组在配种后第 14 天和第 15 天给药。所有奶牛在出现发情迹象后自然配种。配种后 60 天通过直肠触诊进行妊娠诊断。在第二阶段，通过每天两次的视觉观察监测奶牛的发情行为。用 FM、阿司匹林和 CG 处理的奶牛的正常发情周期长度分别为 20、23 和 22 天。治疗对埃及奶牛正常发情周期长度没有显著影响（P<0.05）。用 FM 或阿司匹林处理的埃及奶牛中长周期的比例分别为 75%、67.7%和 57.1%，而 CG 中完全没有短周期。FM 或阿司匹林处理的奶牛中没有短周期，但 CG 中有 29%。与 CG 相比，FM 或阿司匹林处理的奶牛的爬跨行为和尾举行为分别为 0 和 33%、25 和 33%。FM、阿司匹林处理和 CG 的受孕或妊娠率分别为 60%、40%和 30%。FM 或阿司匹林处理的奶牛在发情周期的第 14 天和第 21 天的孕激素浓度与 CG 相比没有影响（P<0.05）。综上所述，本研究结果表明，在热季，FM 和阿司匹林的使用对埃及巴尔迪奶牛发情行为的强烈程度和受孕率有有益的影响。
