东地中海地区实验室在世界卫生组织虫媒病毒诊断外部质量评估计划中的表现。
Performance of Eastern Mediterranean Region laboratories in the World Health Organization external quality assessment programme for arbovirus diagnostics.
机构信息
World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.
World Health Organization, Lyon, France.
出版信息
East Mediterr Health J. 2020 May 21;26(5):616-619. doi: 10.26719/emhj.20.015.
BACKGROUND
Arboviruses such as dengue virus, yellow fever virus, Zika virus and chikungunya virus are major threats to human health globally, including countries in the Eastern Mediterranean Region (EMR).
AIMS
This study aimed to assess laboratory proficiency in EMR countries for detection of dengue virus, yellow fever virus, Zika virus and chikungunya virus.
METHODS
A global external quality assessment programme for arbovirus diagnostics was developed and run in 2016 and 2018. National-level public health laboratories were instructed to apply the polymerase chain reaction detection method on specimen panels containing dengue virus, yellow fever virus, Zika virus and chikungunya virus.
RESULTS
Over both rounds of the programme, 100% of participating EMR laboratories correctly detected yellow fever virus and chikungunya virus, ≥ 84.6% detected dengue fever virus and ≥ 76.9% detected Zika virus.
CONCLUSION
While participating EMR countries demonstrated good proficiency in detecting arboviruses, only half of them were enrolled in the global external quality assessment programme, providing an incomplete picture of regional capacity. Effort should be put into increasing participation in subsequent rounds.
背景
虫媒病毒（如登革热病毒、黄热病病毒、寨卡病毒和基孔肯雅热病毒）是对包括东地中海区域（EMR）国家在内的全球人类健康的重大威胁。
目的
本研究旨在评估 EMR 国家在检测登革热病毒、黄热病病毒、寨卡病毒和基孔肯雅热病毒方面的实验室能力。
方法
于 2016 年和 2018 年制定并开展了一项虫媒病毒诊断全球外部质量评估方案。国家公共卫生实验室被指示应用聚合酶链反应检测方法对包含登革热病毒、黄热病病毒、寨卡病毒和基孔肯雅热病毒的标本进行检测。
结果
在两轮方案中，参与的 EMR 实验室均 100%正确检测出黄热病病毒和基孔肯雅热病毒，≥84.6%检测出登革热病毒，≥76.9%检测出寨卡病毒。
结论
尽管参与的 EMR 国家在检测虫媒病毒方面表现出良好的能力，但只有一半的国家参加了全球外部质量评估方案，这提供了区域能力的不完整情况。应努力增加后续轮次的参与。
Zotero 插件