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髋关节镜术前使用阿片类药物的结果:与阿片类药物未使用患者的比较。

Outcomes of Preoperative Opioid Usage in Hip Arthroscopy: A Comparison With Opioid-Naïve Patients.

机构信息

Division of Sports Medicine, Department of Orthopaedic Surgery, NYU Langone Medical Center, Hospital for Joint Diseases, New York, New York, U.S.A..

Division of Sports Medicine, Department of Orthopaedic Surgery, NYU Langone Medical Center, Hospital for Joint Diseases, New York, New York, U.S.A.

出版信息

Arthroscopy. 2020 Nov;36(11):2832-2839.e1. doi: 10.1016/j.arthro.2020.06.005. Epub 2020 Jun 15.

Abstract

PURPOSE

To compare postoperative outcomes between opioid-naïve patients and patients with a history of preoperative opioid usage undergoing hip arthroscopy. The secondary purpose is to determine whether preoperative opioid users consumed more oral morphine milligram equivalents than opioid-naïve patients following surgery.

METHODS

This is a single-center, retrospective analysis comparing outcomes and postoperative opioid usage between patients with and without a history of preoperative opioid use. Inclusion criteria included patients ≥18 years, Tönnis grade 0 or 1, imaging consistent with FAI or labral pathology, and a diagnosis of symptomatic FAI requiring hip arthroscopy. Patient outcomes were compared throughout a 2-year follow-up using the modified Harris Hip Score, Nonarthritic Hip Score, and visual analog scale (VAS).

RESULTS

In total, 17 patients were evaluated in each cohort. The mean age of the study cohort and control cohort were 52.0 ± 9.4 years and 51.2 ± 12.2 years, respectively. Female patients were 58.8% (n = 10) of both cohorts. Non-naïve patients had a lower preoperative Nonarthritic Hip Score (P = .05) and a greater VAS at their 6-month and 1-year (P < .001) postoperative visits. Naïve patients reported greater modified Harris Hip Scores 2 years postoperatively (P < .001). The study cohort was prescribed greater levels of oral morphine equivalents at the postoperative 1-year visit (P = .05). Opioid-naïve patients were more likely to reach minimally clinically important difference and patient acceptable symptom state of VAS at a faster rate. At the 2-year follow-up, 11.8% of opioid-naïve patients continued to take opioids compared with 58.8% from the non-naïve group for persistent hip pain (P < .001).

CONCLUSIONS

We determined that preoperative opioid usage in patients undergoing hip arthroscopy is associated with inferior outcomes compared with opioid-naïve patients. In addition, preoperative opioid users are likely to continue the use of opioid medications postoperatively and at greater doses than opioid-naïve patients.

LEVEL OF EVIDENCE

3, retrospective comparative study.

摘要

目的

比较初次接受髋关节镜手术的阿片类药物未使用者与术前有阿片类药物使用史患者的术后结果。次要目的是确定术后阿片类药物使用者的口服吗啡毫克当量是否超过阿片类药物未使用者。

方法

这是一项单中心回顾性分析,比较了有和无术前阿片类药物使用史患者的结局和术后阿片类药物使用情况。纳入标准包括年龄≥ 18 岁、Tönnis 分级 0 或 1、影像学检查符合 FA I 或盂唇病变、有症状的 FA I 需要行髋关节镜手术。使用改良 Harris 髋关节评分、非关节炎髋关节评分和视觉模拟评分(VAS)在 2 年的随访期间比较患者的结果。

结果

在每个队列中均评估了 17 例患者。研究队列和对照组的平均年龄分别为 52.0±9.4 岁和 51.2±12.2 岁。女性患者分别占两个队列的 58.8%(n=10)。非初次使用者术前非关节炎髋关节评分较低(P=0.05),术后 6 个月和 1 年 VAS 评分较高(P<0.001)。初次使用者术后 2 年改良 Harris 髋关节评分更高(P<0.001)。研究队列在术后 1 年就诊时开出处方的口服吗啡等效物水平更高(P=0.05)。初次使用者更快达到 VAS 的最小临床重要差异和患者可接受的症状状态。在 2 年的随访中,11.8%的初次使用者继续服用阿片类药物,而非初次使用者中仍有 58.8%的患者因髋关节疼痛持续而继续服用阿片类药物(P<0.001)。

结论

我们发现髋关节镜手术患者术前使用阿片类药物与初次使用者相比,结果较差。此外,术前使用阿片类药物的患者术后更有可能继续使用阿片类药物,且剂量大于初次使用者。

证据水平

3,回顾性比较研究。

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