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韩国腘窝囊肿的患病率及其与膝关节骨关节炎严重程度的关联。

The prevalence of fabella and its association with the osteoarthritic severity of the knee in Korea.

作者信息

Hur Jin-Wuk, Lee Seunghun, Jun Jae-Bum

机构信息

Division of Rheumatology, Eulji University of Internal Medicine, Seoul, Republic of Korea.

Department of Radiology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea.

出版信息

Clin Rheumatol. 2020 Dec;39(12):3625-3629. doi: 10.1007/s10067-020-05078-4. Epub 2020 Jun 18.

Abstract

The clinical relevance of the fabella, a sesamoid bone, has recently been investigated. Although many studies have documented the prevalence of the fabella, few large-scale studies have been conducted in an Asian, especially Korean, population. We conducted a retrospective survey of Koreans to determine the prevalence and distribution of the fabella and its association with osteoarthritic severity of the knee. From June 2016 to August 2017, a total of 2243 people who visited a rheumatology clinic for musculoskeletal evaluation was consecutively recruited. A total of 2126 subjects (1634 females and 492 males) was finally registered and analysed. Anteroposterior and lateral radiographs of both knees were analysed for presence, number and distribution of fabellae and Kellgren-Lawrence grade. The prevalence of the fabella was 57.2% (57.5% for females, 56.1% for males). Among subjects with a fabella, 21.2% had a unilateral distribution, and 78.8% had a bilateral distribution. The number of fabella was correlated with increasing age (r = 0.169, p < 0.001). In the group of subjects with a fabella, the Kellgren-Lawrence grade was significantly higher than in the group without a fabella (2.64 ± 1.38 vs. 1.89 ± 1.54, p < 0.001). The prevalence of fabella in Koreans was relatively high compared with the findings of previous studies, irrespective of the country studied or methodology used. The number of fabellae tended to increase with age. The osteoarthritic severity of the knee appeared worse in the group with a fabella. Key Points • The radiographical prevalence rate of fabella in Korea was about 58%, higher than the previous results. • The prevalence of fabella increased as the age of the subject increased regardless of gender. • The association between fabella and osteoarthritis is strongly suspected because the osteoarthritic changes in the knee of the subjects with fabella are significantly higher than in the subjects without fabella.

摘要

籽骨腘豆骨的临床相关性最近已得到研究。尽管许多研究记录了腘豆骨的患病率,但针对亚洲人群,尤其是韩国人群进行的大规模研究却很少。我们对韩国人进行了一项回顾性调查,以确定腘豆骨的患病率、分布情况及其与膝关节骨关节炎严重程度的关联。2016年6月至2017年8月,连续招募了总共2243名因肌肉骨骼问题前往风湿病诊所进行评估的患者。最终登记并分析了2126名受试者(1634名女性和492名男性)。对双膝的前后位和侧位X线片进行分析,以确定腘豆骨的存在、数量和分布以及凯尔格伦-劳伦斯分级。腘豆骨的患病率为57.2%(女性为57.5%,男性为56.1%)。在有腘豆骨的受试者中,21.2%为单侧分布,78.8%为双侧分布。腘豆骨的数量与年龄增长相关(r = 0.169,p < 0.001)。在有腘豆骨的受试者组中,凯尔格伦-劳伦斯分级显著高于没有腘豆骨的受试者组(2.64±1.38 vs. 1.89±1.54,p < 0.001)。与先前研究的结果相比,韩国人腘豆骨的患病率相对较高,无论所研究的国家或使用的方法如何。腘豆骨的数量倾向于随年龄增加。有腘豆骨的组中膝关节的骨关节炎严重程度似乎更差。要点• 韩国腘豆骨的X线患病率约为58%,高于先前结果。• 无论性别如何,腘豆骨的患病率随受试者年龄的增加而增加。• 强烈怀疑腘豆骨与骨关节炎之间存在关联,因为有腘豆骨的受试者膝关节的骨关节炎变化明显高于没有腘豆骨的受试者。

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