Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS, Vile Parle [W], Mumbai, 400056, Maharashtra, India.
Carbohydr Polym. 2020 Aug 15;242:116430. doi: 10.1016/j.carbpol.2020.116430. Epub 2020 May 17.
Cyclodextrins are cyclic oligosaccharides, having tyroid shape of the molecule which has a hydrophobic cavity and outer hydrophilic surface. This characteristic feature of the dextrins allows it to function as a functionalizing as well as a stabilizing agent. Polymer nanocomposites are nanoscale composites of polymers with enhanced and synergized properties of its components and have been known to have applications in various fields of chemistry, biomedical, pharmaceutical and environmental purposes to name a few. To impart specificity, thermal, mechanical stability, resistance to solvents and biodegradability to the polymers, cyclodextrins have been incorporated in the nanocomposites. The utilization of the aforementioned properties of cyclodextrins to the polymer nanocomposites, implications of the incorporation of cyclodextrins to polymer nanocomposites and their subsequent applications in various fields have been discussed in this review systematically, using PRISMA guidelines.
环糊精是环状低聚糖，分子形状为甲状腺状，具有疏水性内腔和外亲水性表面。这种特性使环糊精能够充当功能化和稳定化试剂。聚合物纳米复合材料是聚合物的纳米级复合材料，具有增强和协同的成分性能，并且已经在化学、生物医学、制药和环境等各个领域得到了应用。为了使聚合物具有特异性、热稳定性、机械稳定性、耐溶剂性和生物降解性，已经将环糊精掺入纳米复合材料中。本文使用 PRISMA 指南，系统地讨论了将上述环糊精特性应用于聚合物纳米复合材料，以及将环糊精掺入聚合物纳米复合材料及其随后在各个领域的应用。
