Mackenbach J P, Kunst A E, Looman C W, Habbema J D, van der Maas P J
Department of Public Health and Social Medicine, Erasmus University Rotterdam, The Netherlands.
J Epidemiol Community Health. 1988 Dec;42(4):325-32. doi: 10.1136/jech.42.4.325.
In The Netherlands, as in many other countries, important geographical variation in mortality from conditions amenable to medical intervention exists. Associations with a number of simple medical care supply characteristics (general practitioner density, hospital bed density, and percentage of regional hospital beds located in university and small hospitals) are generally weak and inconsistent, both before and after controlling for possible confounding factors. We explored one of the possible reasons for this lack of consistency, which is the time dependency of the relationship between medical care supply and avoidable mortality. A comparison of associations in four time periods (1950-54, 1960-64, 1970-74 and 1980-84) shows that the percentage of variance in regional mortality levels which can be "explained" by the medical care supply variables has changed over time. Although the patterns of change differ little from what one would expect on the basis of the time of introduction of medical care innovations, the exact nature of the associations is puzzling. Apart from some expected negative associations between mortality and the presence of university hospitals, we also found a few unexpected positive associations with general practitioner density. Possible explanations for these findings are discussed, and it is concluded that further study is necessary to reveal the causes of a higher or lower mortality level for conditions considered to be amenable to medical intervention.
与许多其他国家一样,荷兰在可通过医疗干预改善的疾病死亡率方面存在显著的地理差异。在控制了可能的混杂因素之前和之后,与一些简单的医疗服务供应特征(全科医生密度、医院床位密度以及大学医院和小型医院的区域医院床位百分比)之间的关联通常都很微弱且不一致。我们探究了这种缺乏一致性的一个可能原因,即医疗服务供应与可避免死亡率之间关系的时间依赖性。对四个时间段(1950 - 54年、1960 - 64年、1970 - 74年和1980 - 84年)的关联进行比较表明,可由医疗服务供应变量“解释”的区域死亡率水平方差百分比随时间发生了变化。尽管变化模式与基于医疗创新引入时间的预期差异不大,但关联的确切性质令人费解。除了死亡率与大学医院存在一些预期的负相关外,我们还发现了一些与全科医生密度意外的正相关。讨论了这些发现的可能解释,并得出结论认为有必要进行进一步研究以揭示被认为可通过医疗干预改善的疾病死亡率较高或较低的原因。