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对于采用闭合复位治疗的发育性髋关节发育不良儿童,股骨头大小与股骨近端骨骺缺血性坏死的发生率是否相关?

Does the size of the femoral head correlate with the incidence of avascular necrosis of the proximal femoral epiphysis in children with developmental dysplasia of the hip treated by closed reduction?

作者信息

Wu JianPing, Yuan Zhe, Li JingChun, Zhu MingWei, Canavese Federico, Xun FuXing, Li YiQiang, Xu HongWen

机构信息

Department of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.

出版信息

J Child Orthop. 2020 Jun 1;14(3):175-183. doi: 10.1302/1863-2548.14.190176.

Abstract

PURPOSE

The purpose of this study was to identify if any correlation between size of the proximal femoral epiphysis and avascular necrosis (AVN) exists.

METHODS

We retrospectively reviewed 111 patients with developmental dysplasia of the hip treated by closed reduction (124 hips). The diameter and height of both femoral head and ossific nucleus were assessed on preoperative MRI.

RESULTS

The diameter and the height of the femoral head as well as of the ossific nucleus of the contralateral side were significantly greater than the dislocated side. AVN occurred in 21 (16.9%) out of 124 hips. The rate of AVN gradually decreased with age: 30.0% at six to 12 months, 18.2% at 12 to 18 months and 3.7% at 18 to 24 months. Spearman correlation analysis showed that age is negatively correlated with the incidence of AVN (r = -0.274; p = 0.002) and the diameter of the femoral head has a significantly negative association with the incidence of AVN (r = -0.287; p = 0.001). No significant association was observed between the incidence of AVN and height of the femoral head or size of the ossific nucleus. Hips with AVN were significantly smaller than hips without AVN.

CONCLUSIONS

The size of both the femoral head and the ossific nucleus increase with age although the dislocated femoral head is smaller compared with the contralateral side. The diameter of the femoral head and not the size of the ossific nucleus negatively correlate with the risk of AVN, with a bigger femoral head showing lower risk of AVN.

LEVEL OF EVIDENCE

III.

摘要

目的

本研究旨在确定股骨近端骨骺大小与缺血性坏死(AVN)之间是否存在任何相关性。

方法

我们回顾性分析了111例接受闭合复位治疗的发育性髋关节发育不良患者(124髋)。术前通过MRI评估股骨头和骨化核的直径及高度。

结果

对侧股骨头及骨化核的直径和高度均显著大于脱位侧。124髋中有21髋(16.9%)发生了AVN。AVN的发生率随年龄逐渐降低:6至12个月时为30.0%,12至18个月时为18.2%,18至24个月时为3.7%。Spearman相关性分析显示,年龄与AVN的发生率呈负相关(r = -0.274;p = 0.002),股骨头直径与AVN的发生率呈显著负相关(r = -0.287;p = 0.001)。未观察到AVN的发生率与股骨头高度或骨化核大小之间存在显著关联。发生AVN的髋关节明显小于未发生AVN的髋关节。

结论

尽管脱位的股骨头比另一侧小,但股骨头和骨化核的大小均随年龄增加。股骨头直径而非骨化核大小与AVN风险呈负相关,股骨头越大,AVN风险越低。

证据水平

III级。

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