Li Qiaoliang, Li Shiyu, Liu Xinyu, He Zhuoying, Wang Tao, Xu Ying, Guan Huimin, Chen Runmin, Qi Suwen, Wang Feng
National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, School of Medicine, Shenzhen University, Xueyuan Avenue, Nanshan District, Shenzhen, 518071, China.
Department of Clinical Laboratory, Shenzhen Baoan Women's and Children's Hospital, Shenzhen, 518071, China.
Med Phys. 2020 Sep;47(9):4212-4222. doi: 10.1002/mp.14352. Epub 2020 Jul 18.
PURPOSE: To automate the detection and identification of visible components in feces for early diagnosis of gastrointestinal diseases, we propose FecalNet, a method using multiple deep neural networks. METHODS: FecalNet uses the ResNet152 residual network to extract and learn the characteristics of visible components in fecal microscopic images, acquire feature maps in combination with the feature pyramid network, apply the full convolutional network to classify and locate the fecal components, and implement the improved focal loss function to reoptimize the classification results. This allowed the complete automation of the detection and identification of the visible components in feces. RESULTS: We validated this method using a fecal database of 1,122 patients. The results indicated a mean average precision (mAP) of 92.16% and an average recall (AR) of 93.56%. The average precision (AP) and AR of erythrocyte, leukocyte, intestinal mucosal epithelial cells, hookworm eggs, ascarid eggs, and whipworm eggs were 92.82% and 93.38%, 93.99% and 96.11%, 90.71% and 92.41%, 89.95% and 93.88%, 96.90% and 91.21%, and 88.61% and 94.37%, respectively. The average times required by the GPU and the CPU to analyze a fecal microscopic image are approximately 0.14 and 1.02 s, respectively. CONCLUSION: FecalNet can automate the detection and identification of visible components in feces. It also provides a detection and identification framework for detecting several other types of cells in clinical practice.
目的:为实现粪便中可见成分的自动检测与识别以用于胃肠道疾病的早期诊断,我们提出了FecalNet,一种使用多个深度神经网络的方法。 方法:FecalNet使用ResNet152残差网络来提取和学习粪便显微图像中可见成分的特征,结合特征金字塔网络获取特征图,应用全卷积网络对粪便成分进行分类和定位,并实现改进的焦点损失函数以重新优化分类结果。这实现了粪便中可见成分检测与识别的完全自动化。 结果:我们使用一个包含1122名患者的粪便数据库对该方法进行了验证。结果表明平均精度均值(mAP)为92.16%,平均召回率(AR)为93.
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