Department of Pharmacy, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj-8100, Bangladesh.
Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran.
Cell Mol Biol (Noisy-le-grand). 2020 Jun 25;66(4):28-32.
Metallo-drugs have gained a huge attention among scientific community in the couple years. These drugs types have become important compounds in cancer therapy, where, for instance, platinum complexes are being used against many tumors worldwide. Nonetheless, to p-cymene metallo-derivatives a promising anticancer potential has also been increasingly proposed. In this sense, the present review aims to provide an in-depth revision of p-cymene metallo-drugs possible mechanisms of anticancer action for upcoming pharmaceutical and biotechnological prospects. p-cymene metallo-derivatives have revealed very interesting anticancer activities in various test systems, including cancer cells, being thus worth of note to deepen knowledge through clinical trials on their upcoming use for cancer chemotherapy combination.
金属药物在近几年引起了科学界的极大关注。这些药物类型已成为癌症治疗中的重要化合物，例如，铂配合物在全球范围内被用于治疗多种肿瘤。尽管如此，对 p-伞花烃金属衍生物也提出了越来越有前途的抗癌潜力。在这个意义上，本综述旨在为 p-伞花烃金属药物的抗癌作用的可能机制提供深入的修订，以展望未来药物和生物技术的前景。p-伞花烃金属衍生物在各种测试系统中表现出非常有趣的抗癌活性，包括癌细胞，因此值得注意的是，通过临床试验加深对其即将用于癌症化疗联合应用的认识。
