评价各种冲洗激活系统从根管系统中清除细菌的效果：一项随机对照单盲试验。

Evaluation of various irrigation activation systems to eliminate bacteria from the root canal system: A randomized controlled single blinded trial.

机构信息

Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

出版信息

J Dent. 2020 Aug;99:103412. doi: 10.1016/j.jdent.2020.103412. Epub 2020 Jun 22.

DOI:10.1016/j.jdent.2020.103412

PMID:32585261

Abstract

OBJECTIVE

To evaluate the effect of NaOCl irrigant activation using passive ultrasonic activation, F-files, XP-endo Finisher files and or needle irrigation alone on the reduction of intracanal bacteria from root canals in teeth undergoing root canal treatment.

METHODS

Eighty patients with asymptomatic apical periodontitis were randomly divided into four groups. Access cavities were prepared and pre-treatment samples were taken (S1). Canals were then prepared and post-instrumentation samples (S2) taken. NaOCl was then activated with the various irrigant activation systems and post-irrigation samples (S3) taken. The samples were processed and colony forming units (CFUs) of bacteria were determined. The reduction in CFUs among the experimental groups were analysed using the Kruskal Wallis test and pairwise comparisons with the Mann-Whitney test. The Friedman test was used to compare the differences in the reduction of CFUs within the groups.

RESULTS

Overall, for all groups there was a significant reduction in the CFUs from S1 to S2 (P < 0.05) and from S2 to S3 (P < 0.05). Both XP-endo Finisher and passive ultrasonic activation techniques were associated with the greatest reduction in CFUs with no significant difference between them (P = 0.24). However, both were associated with significantly lower CFUs when compared to F-file activation and needle irrigation (P < 0.05). F-file activation reduced the CFUs significantly more compared to needle irrigation (P = 0.04).

CONCLUSIONS

XP-endo Finisher file activation and passive ultrasonic activation were equivalent in terms of reduction in CFUs. F-file activation did not reduce the CFUs to the same extent as the XP-endo Finisher file and ultrasonic activation but reduced the CFUs more than needle irrigation.

CLINICAL SIGNIFICANCE

The present study highlights the effect of new XP-endo Finisher file and passive ultrasonic activation in reducing the bacterial load from the root canal system which is important for the success of root canal treatment.

摘要

目的

评估使用被动超声激活、F 锉、XP-endo 锉和/或单针冲洗对根管内细菌的清除效果，用于治疗有症状的根尖周炎患者。

方法

将 80 名患有无症状根尖周炎的患者随机分为四组。制备开髓腔并采集预处理样本（S1）。然后预备根管并采集根管预备样本（S2）。随后使用各种冲洗激活系统激活 NaOCl 并采集冲洗后样本（S3）。处理样本并测定细菌的菌落形成单位（CFU）。使用 Kruskal-Wallis 检验分析实验组之间 CFU 的减少情况，并使用 Mann-Whitney 检验进行两两比较。使用 Friedman 检验比较组内 CFU 减少的差异。

结果

总体而言，所有组从 S1 到 S2（P<0.05）和从 S2 到 S3（P<0.05）CFU 均显著减少。XP-endo 锉和被动超声激活技术都与 CFU 减少量最大相关，且两者之间无显著差异（P=0.24）。然而，与 F 锉激活和单针冲洗相比，两者的 CFU 均显著更低（P<0.05）。F 锉激活与单针冲洗相比，显著减少了 CFU（P=0.04）。