Andrews H, Wyke J, Lane M, Clay J, Keighley M R, Allan R N
Department of Gastroenterology, General Hospital, Birmingham.
Gut. 1988 Mar;29(3):332-5. doi: 10.1136/gut.29.3.332.
Fifty male patients with proctitis were examined and the clinical, microbiological, serological and proctological features compared with 51 known male homosexuals attending the genitourinary (GU) clinic at the same hospital. The homosexuals had a short history of bowel symptoms, minor sigmoidoscopic and histological changes on rectal biopsy and many positive serological markers of sexually transmitted infection. There was some evidence of sexually transmitted disease in the IBD patients and three were homosexuals. IgG antibodies were positive for chlamydia trachomatis (n = 10) and hepatitis A (n = 7). One had a positive screening test for syphilis. Stool examination and rectal swab cultures were positive in two patients for cryptosporidium and cytomegalovirus respectively. Gastroenterologists must be aware of the possibility of specific infection in IBD patients and a clinical history should include sexual preferences and practices. If homosexuality is admitted, specific infection must be sought and excluded.
对50例男性直肠炎患者进行了检查，并将其临床、微生物学、血清学和直肠学特征与同一家医院泌尿生殖科（GU）门诊的51名已知男性同性恋者进行了比较。同性恋者肠道症状病史较短，直肠活检时乙状结肠镜检查和组织学变化轻微，且有许多性传播感染的阳性血清学标志物。炎症性肠病（IBD）患者中有一些性传播疾病的证据，其中3人是同性恋者。沙眼衣原体IgG抗体阳性者10例，甲型肝炎IgG抗体阳性者7例。1例梅毒筛查试验呈阳性。两名患者的粪便检查和直肠拭子培养分别发现隐孢子虫和巨细胞病毒呈阳性。胃肠病学家必须意识到IBD患者发生特定感染的可能性，临床病史应包括性取向和性行为。如果承认患者为同性恋者，则必须寻找并排除特定感染。
