Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.
Br J Cancer. 2020 Sep;123(6):871-873. doi: 10.1038/s41416-020-0926-3. Epub 2020 Jun 26.
Oncological phototherapy, including current photodynamic therapy (PDT), developmental photoactivated chemotherapy (PACT) and photothermal therapy (PTT), shows promising photo-efficacy for superficial and internal tumours. The dual application of light and photochemotherapeutic agents allows accurate cancer targeting, low invasiveness and novel mechanisms of action. Current advances in new light sources and photoactive agents are encouraging for future development.
肿瘤光疗,包括当前的光动力疗法(PDT)、发展中的光激活化疗(PACT)和光热疗法(PTT),在治疗浅表和内部肿瘤方面显示出有前景的光疗效果。光和光化疗剂的双重应用允许精确的癌症靶向、低侵入性和新的作用机制。新光源和光活性试剂的当前进展为未来的发展提供了鼓舞。