Price M L, Walmsley A, Swaine C, Ponte J
Queen Charlotte's Maternity Hospital, London.
Anaesthesia. 1988 Mar;43 Suppl:84-7. doi: 10.1111/j.1365-2044.1988.tb09081.x.
A total intravenous anaesthetic technique with a propofol infusion for maintenance of anaesthesia was compared with an inhalational technique that used oxygen, nitrous oxide and enflurane in 98 unpremedicated patients who presented for day case surgery. Overall quality of anaesthesia during induction and maintenance was comparable in both groups. Quality of maintenance of anaesthesia in the propofol group was improved by an increase of the initial infusion rate from 12 to 15 mg/kg/hour. There was a larger decrease in arterial blood pressure after induction in the propofol group but no difference in blood pressure between the groups during maintenance. Recovery times and scores using the Steward scoring system were not significantly different. Nausea and vomiting were slightly less frequent in the propofol group.
在98例未接受术前用药、拟行日间手术的患者中,比较了采用丙泊酚输注维持麻醉的全静脉麻醉技术与使用氧气、氧化亚氮和安氟醚的吸入麻醉技术。两组在诱导和维持麻醉期间的总体麻醉质量相当。丙泊酚组将初始输注速率从12毫克/千克/小时提高到15毫克/千克/小时后,麻醉维持质量得到改善。丙泊酚组诱导后动脉血压下降幅度更大,但维持期间两组血压无差异。使用Steward评分系统的恢复时间和评分无显著差异。丙泊酚组恶心和呕吐的发生率略低。