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商业保险人群中阿片类物质使用障碍的门诊治疗:药物及心理社会治疗的应用

Outpatient care for opioid use disorder among the commercially insured: Use of medication and psychosocial treatment.

作者信息

Busch Alisa B, Greenfield Shelly F, Reif Sharon, Normand Sharon-Lise T, Huskamp Haiden A

机构信息

Department of Health Care Policy, Harvard Medical School, Boston, MA, United States of America.

McLean Hospital, Belmont, MA, United States of America.

出版信息

J Subst Abuse Treat. 2020 Aug;115:108040. doi: 10.1016/j.jsat.2020.108040. Epub 2020 May 22.

Abstract

BACKGROUND

Evidence-based outpatient treatment for opioid use disorder (OUD) consists of medications that treat OUD (MOUD) and psychosocial treatments (e.g., psychotherapy or counseling, case management). Prior studies have not examined the use of these components of care in a commercially insured population.

METHODS

We analyzed claims data from a large national commercial insurer of enrollees age 17-64 identified with OUD (2008-2016, N = 87,877 persons and 122,708 person-years). Multinomial logistic regression models identified factors associated with receiving in a given year: 1) both MOUD and psychosocial visits, 2) MOUD without psychosocial visits, 3) psychosocial visits without MOUD, or 4) neither. We estimated predicted probabilities for key variables of interest.

RESULTS

Identification of OUD nearly tripled during the observation period (0.17% in 2008, 0.45% in 2016). Among person-years identified as having OUD, 36.3% included MOUD (8.1% both MOUD and psychosocial visits and 28.2% MOUD without psychosocial visits). In adjusted analyses, women had a lower probability of receiving either treatment alone or in combination (e.g.,MOUD plus psychosocial visits: women = 6.7% [6.5%-6.9%] vs. men = 9.2% [9.0%-9.4%]). Moderate/severe vs. mild OUD was associated with a higher probability of receiving MOUD (e.g., MOUD plus psychosocial visits: 8.7% [8.6%-8.9%] vs. 0.9% [0.7%-1.0%]). In contrast, an OUD overdose was associated with a greater probability of receiving neither treatment (78.2% [77.4%-79.0%] vs. 55.5% [55.2%-55.8%]). Over time, the probability of receiving each MOUD and psychosocial treatment category increased relative to 2008, but reached a peak and then plateaued or declined, by the end of the study period.

CONCLUSIONS

A significant treatment gap exists among individuals identified with OUD in this commercially insured population, with greater risks of receiving no treatment for women and for individuals with mild versus moderate or severe OUD. Overdose is associated with receiving neither MOUD nor psychosocial treatment. While treated prevalence initially increased relative to 2008, rates of treatment subsequently plateaued. Additional study and monitoring to elucidate barriers to OUD treatment in commercially insured populations are warranted.

摘要

背景

阿片类物质使用障碍(OUD)的循证门诊治疗包括治疗OUD的药物(MOUD)和心理社会治疗(如心理治疗或咨询、病例管理)。既往研究未考察这些护理组成部分在商业保险人群中的使用情况。

方法

我们分析了一家大型全国性商业保险公司的索赔数据,该公司的参保者年龄在17 - 64岁之间,被确诊患有OUD(2008 - 2016年,N = 87877人,122708人年)。多项逻辑回归模型确定了与在给定年份接受以下治疗相关的因素:1)MOUD和心理社会诊疗均接受;2)仅接受MOUD而无心理社会诊疗;3)仅接受心理社会诊疗而无MOUD;或4)两者均未接受。我们估计了关键感兴趣变量的预测概率。

结果

在观察期内,OUD的确诊率几乎增长了两倍(2008年为0.17%,2016年为0.45%)。在被确诊患有OUD的人年中,36.3%接受了MOUD治疗(8.1%同时接受MOUD和心理社会诊疗,28.2%仅接受MOUD而无心理社会诊疗)。在调整分析中,女性单独接受任何一种治疗或联合治疗的概率较低(例如,MOUD加心理社会诊疗:女性 = 6.7% [6.5% - 6.9%],男性 = 9.2% [9.0% - 9.4%])。中度/重度与轻度OUD相比,接受MOUD治疗的概率更高(例如,MOUD加心理社会诊疗:8.7% [8.6% - 8.9%],而轻度为0.9% [0.7% - 1.0%])。相比之下,OUD过量用药与两种治疗均未接受的概率更高相关(78.2% [77.4% - 79.0%],而未过量用药为55.5% [55.2% - 55.8%])。随着时间推移,相对于2008年,接受每种MOUD和心理社会治疗类别的概率均有所增加,但到研究期末达到峰值,随后趋于平稳或下降。

结论

在这个商业保险人群中,确诊患有OUD的个体存在显著的治疗差距,女性以及轻度与中度或重度OUD患者未接受治疗的风险更高。过量用药与未接受MOUD和心理社会治疗均相关。虽然相对于2008年,接受治疗的患病率最初有所增加,但随后治疗率趋于平稳。有必要进行进一步研究和监测,以阐明商业保险人群中OUD治疗的障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/7687676/bb970bd15f90/nihms-1598002-f0001.jpg

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