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印度医护人员中流感样症状和新冠病毒病的患病率

Prevalence of Flu-like Symptoms and COVID-19 in Healthcare Workers from India.

作者信息

Jha Sujeet, Soni Aakriti, Siddiqui Samreen, Batra Nitish, Goel Nikita, Dey Sneha, Budhiraja Sandeep, Naithani Rahul

机构信息

Institute of Endocrinology, Diabetes, and Metabolism, Max Healthcare, New Delhi.

Internal Medicine, Max Healthcare, New Delhi.

出版信息

J Assoc Physicians India. 2020 Jul;68(7):27-29.

PMID:32602677
Abstract

BACKGROUND

The current COVID-19 pandemic is unprecedented. As the numbers expand exponentially, a paucity of data regarding health care workers (HCWs), who are at the forefront of this disaster, exists. Hence we decided to conduct a study amongst the HCWs to determine the prevalence and risk factor stratification.

METHODS

This was an online questionnaire-based survey of healthcare workers conducted at Max Super Speciality Hospital, Saket, New Delhi, India from 23rd March to 30th April 2020. Data on flu-like symptoms, travel history, posting in high-risk or low risk zones, and prophylactic drugs was collected.

RESULTS

Out of the 18000 HCWs who were approached 4403 responded and adequate data of 3667 was available for analysis. 14.7% had flu-like symptoms. 1.8% (20/1113) of the participants tested were positive for the virus. HCWs posted in the high-risk zones had more symptoms than those working in low-risk zones (169/539, 31.4% vs 679/3128, 21.7%), p<0.001; but no difference in COVID-19 positivity rates (p=0.849). Symptomatic HCWs had higher positivity (10/193, 5.2%) than the asymptomatic ones (10/920, 1.1%), p=0.001. HCQ was taken by 755/1113 (67.8%) people and 14 (1.9%) of these reported positive for the virus.

CONCLUSION

This is the first study on healthcare workers from India to the best of our knowledge. Our findings suggest that posting in a high-risk zone with adequate PPE does not pose higher risk to the HCWs. Moreover, HCQ as a prophylactic has no use.

CLINICALTRIALS.GOV IDENTIFIER: NCT04339608.

摘要

背景

当前的新冠疫情是前所未有的。随着感染人数呈指数级增长,关于身处这场灾难前沿的医护人员的数据却很匮乏。因此,我们决定在医护人员中开展一项研究,以确定患病率及风险因素分层。

方法

这是一项基于在线问卷的对医护人员的调查,于2020年3月23日至4月30日在印度新德里萨克特的马克斯超级专科医院进行。收集了有关流感样症状、旅行史、在高风险或低风险区域的工作岗位以及预防性用药的数据。

结果

在被邀请的18000名医护人员中,4403人做出了回应,3667人的数据足够用于分析。14.7%的人有流感样症状。1.8%(20/1113)的受测参与者病毒检测呈阳性。在高风险区域工作的医护人员比在低风险区域工作的医护人员有更多症状(169/539,31.4%对679/3128,21.7%),p<0.001;但新冠病毒阳性率无差异(p=0.849)。有症状的医护人员阳性率(10/193,5.2%)高于无症状者(10/920,1.1%),p=0.001。755/1113(67.8%)的人服用了羟氯喹,其中14人(1.9%)病毒检测呈阳性。

结论

据我们所知,这是第一项针对印度医护人员的研究。我们的研究结果表明,在配备充足个人防护装备的高风险区域工作,并不会给医护人员带来更高风险。此外,羟氯喹作为预防用药并无作用。

临床试验注册编号

NCT04339608

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