在一个中国老年队列中，与性别和年龄相关的轻度认知障碍与低握力有关。
Sex- and age-specific mild cognitive impairment is associated with low hand grip strength in an older Chinese cohort.
机构信息
Nutritional Department of Anhui No. 2 Provincial People's Hospital, Hefei, Anhui, China.
School of Public Health, Department of Nutrition and Food Hygiene, Anhui Medical University, Anhui Hefei, China.
出版信息
J Int Med Res. 2020 Jun;48(6):300060520933051. doi: 10.1177/0300060520933051.
BACKGROUND
Few studies have demonstrated the impact of characteristics like age and sex on the association between hand grip strength (HGS) and mild cognitive impairment (MCI). In this cross-sectional study, we aimed to examine the effects of sex and age on the relationship between HGS and MCI.
METHODS
We enrolled older adults age ≥60 years (n = 1009) and measured HGS and MCI in all participants. We analyzed the differences in MCI prevalence among the different variables. The role of sex and age in the association between MCI and HGS was analyzed using binary logistic regression.
RESULTS
Women had significantly higher prevalence of MCI than men, as did the older group (age ≥70 years) compared with the younger group (age 60-70 years). In men, the low and middle HGS tertiles were significantly associated with MCI. In contrast, only the low tertile of HGS was associated with MCI in women. In the older group, the low tertile of HGS was significantly associated with MCI, which was not observed in the younger group.
CONCLUSIONS
HGS was associated with MCI in older adults, and this association was stronger in men. HGS may be useful for evaluating MCI in older adults.
背景
很少有研究表明年龄和性别等特征对握力（HGS）与轻度认知障碍（MCI）之间的关联有影响。在这项横断面研究中，我们旨在研究性别和年龄对 HGS 与 MCI 之间关系的影响。
方法
我们纳入了年龄≥60 岁的老年人（n=1009），并对所有参与者进行了 HGS 和 MCI 测量。我们分析了不同变量之间 MCI 患病率的差异。使用二元逻辑回归分析了 MCI 和 HGS 之间的关联中性别和年龄的作用。
结果
女性的 MCI 患病率显著高于男性，年龄≥70 岁的老年人组也显著高于 60-70 岁的老年人组。在男性中，低和中 HGS 三分位与 MCI 显著相关。相比之下，女性只有低 HGS 三分位与 MCI 相关。在老年组中，低 HGS 三分位与 MCI 显著相关，但在年轻组中则没有观察到这种相关性。
结论
HGS 与老年人的 MCI 相关，这种关联在男性中更强。HGS 可能有助于评估老年人的 MCI。
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