Maulika Kohli, BA, is a Doctoral Researcher, San Diego State University/University of California San Diego, Joint Doctoral Program in Clinical Psychology, San Diego, California, USA. Lily Kamalyan, MA, is a Doctoral Researcher, San Diego State University/University of California San Diego, Joint Doctoral Program in Clinical Psychology, San Diego, California, USA. Elizabeth C. Pasipanodya, PhD, is a Postdoctoral Researcher, Santa Clara Valley Medical Center, Rehabilitation Research Center, San Jose, California, USA. Anya Umlauf, MS, is a Senior Statistician, Department of Psychiatry, University of California, San Diego, San Diego, California, USA. Raeanne C. Moore, PhD, is an Associate Professor, Department of Psychiatry, University of California, San Diego, San Diego, California, USA. Scott L. Letendre, MD, is a Professor of Medicine and Psychiatry, Department of Medicine, University of California San Diego, San Diego, California, USA. Dilip V. Jeste, MD, is a Director, Sam and Rose Stein Institute for Research on Aging, University of California San Diego, San Diego, California, USA. David J. Moore, PhD, is a Professor of Psychiatry, Department of Psychiatry, University of California, San Diego, San Diego, California, USA.
J Assoc Nurses AIDS Care. 2020 Sep-Oct;31(5):587-597. doi: 10.1097/JNC.0000000000000184.
We examined how the discrepancy between felt age (FA) and chronological age (CA) differed by HIV serostatus across three age cohorts and related to health-related quality of life (HRQoL). Participants included 119 people living with HIV (PLWH) and 98 uninfected adults, ages 36–65 years. FA was assessed by asking, “How old/young do you feel?” HRQoL was measured using the Medical Outcome Study Short Form Health Survey. Linear regressions examined the interaction between HIV serostatus and HRQoL on FA discrepancy scores (FADS; i.e., difference between CA and FA). 72.3% of PLWH felt younger than their CA, which was lower than the uninfected group (92.9%; < .001). PLWH had lower FADS than the uninfected group ( = .050), particularly in the 46- to 55-year-old cohort ( = .015). The positive association between physical HRQoL and FADS was stronger among PLWH (β = 0.14, = .024). A high proportion of PLWH reported feeling younger than their CA, and this perception was related to higher physical HRQoL.
我们研究了在三个年龄队列中，艾滋病毒血清阳性状态如何导致感知年龄（FA）与实际年龄（CA）之间的差异，并与健康相关的生活质量（HRQoL）相关。参与者包括 119 名艾滋病毒感染者（PLWH）和 98 名未感染者，年龄在 36-65 岁之间。通过询问“您感觉自己几岁/年轻？”来评估 FA。使用医疗结局研究短表健康调查来衡量 HRQoL。线性回归检验了 HIV 血清状态和 HRQoL 与 FA 差异评分（FADS；即 CA 和 FA 之间的差异）之间的相互作用。72.3%的 PLWH 感觉比实际年龄年轻，低于未感染者（92.9%；<.001）。PLWH 的 FADS 低于未感染者（=0.050），尤其是在 46-55 岁年龄组（=0.015）。身体 HRQoL 与 FADS 之间的正相关关系在 PLWH 中更强（β=0.14，=0.024）。相当一部分 PLWH 报告感觉比实际年龄年轻，这种认知与更高的身体 HRQoL 有关。
