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Does Nitrous Oxide Help Veterans With Posttraumatic Stress Disorder? A Case Series.一氧化二氮对创伤后应激障碍退伍军人有帮助吗？病例系列报告。
J Clin Psychiatry. 2020 Jun 30;81(4):20l13393. doi: 10.4088/JCP.20l13393.
2
[Tolerance of nitrous oxide-oxygen sedation for painful procedures in emergency pediatrics: report of 600 cases].
Arch Pediatr. 2002 Nov;9(11):1213-5. doi: 10.1016/s0929-693x(02)00102-1.
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[Analgesia using a (50/50) mixture of nitrous oxide/oxygen in children].[儿童使用氧化亚氮/氧气（50/50）混合气体进行镇痛]
Arch Pediatr. 1999 May;6(5):578-85. doi: 10.1016/s0929-693x(99)80572-7.
4
Pro-Con Debate: Nitrous Oxide for Labor Analgesia.正方与反方观点辩论：一氧化二氮在分娩镇痛中的应用。
Biomed Res Int. 2019 Aug 20;2019:4618798. doi: 10.1155/2019/4618798. eCollection 2019.
5
Postischemic nitrous oxide alone versus intraischemic nitrous oxide in the presence of isoflurane: what it may change for neuroprotection against cerebral stroke in the rat.缺血后单独使用一氧化二氮与在异氟烷存在下缺血期间使用一氧化二氮的比较：这对大鼠脑卒中介导神经保护可能产生的影响。
Anesth Analg. 2005 Aug;101(2):614. doi: 10.1213/01.ANE.0000159020.86959.83.
6
From Dental to Mental Institutions: Asylum-Bound Dentist Zacheus Rogers Oxygenates Nitrous Oxide.
J Anesth Hist. 2017 Oct;3(4):142-143. doi: 10.1016/j.janh.2017.09.003. Epub 2017 Sep 29.
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Nitrous oxide and perioperative outcomes.笑气与围手术期结局。
J Anesth. 2014 Jun;28(3):420-8. doi: 10.1007/s00540-013-1729-y. Epub 2013 Oct 27.
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Nitrous oxide--time to say goodbye!一氧化二氮——是时候说再见了！
J Ayub Med Coll Abbottabad. 2008 Oct-Dec;20(4):1-2.
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Avoidance of nitrous oxide for patients undergoing major surgery: a randomized controlled trial.避免对接受大手术的患者使用氧化亚氮：一项随机对照试验。
Anesthesiology. 2007 Aug;107(2):221-31. doi: 10.1097/01.anes.0000270723.30772.da.
10
An unusual cause of falls in a young woman.一名年轻女性跌倒的罕见原因。
J R Coll Physicians Edinb. 2016 Sep;46(3):160-162. doi: 10.4997/JRCPE.2016.304.

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Examining memory reconsolidation as a mechanism of nitrous oxide's antidepressant action.研究记忆重新巩固作为一氧化二氮抗抑郁作用的一种机制。
Neuropsychopharmacology. 2025 Mar;50(4):609-617. doi: 10.1038/s41386-024-02049-0. Epub 2025 Jan 17.
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Nitrous Oxide Alters Functional Connectivity in Medial Limbic Structures in Treatment-Resistant Major Depression.一氧化二氮改变难治性重度抑郁症患者内侧边缘结构的功能连接性。
medRxiv. 2024 Aug 17:2024.08.12.24311729. doi: 10.1101/2024.08.12.24311729.
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Synthetic surprise as the foundation of the psychedelic experience.合成的惊喜是迷幻体验的基础。
Neurosci Biobehav Rev. 2024 Feb;157:105538. doi: 10.1016/j.neubiorev.2024.105538. Epub 2024 Jan 12.
4
Persistent Brain Connectivity Changes in Healthy Volunteers Following Nitrous Oxide Inhalation.健康志愿者吸入一氧化二氮后大脑连接性的持续变化
Biol Psychiatry Glob Open Sci. 2023 Feb 2;3(4):698-704. doi: 10.1016/j.bpsgos.2023.01.006. eCollection 2023 Oct.
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Treatment of Posttraumatic Stress Disorder: A State-of-the-art Review.创伤后应激障碍的治疗：最新综述。
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What is better for psychiatry: Titrated or fixed concentrations of nitrous oxide?对于精神病学而言，哪种更好：滴定浓度还是固定浓度的一氧化二氮？
Front Psychiatry. 2022 Aug 22;13:773190. doi: 10.3389/fpsyt.2022.773190. eCollection 2022.

本文引用的文献

1
First-line Psychotherapies for Military-Related PTSD.针对与军事相关的创伤后应激障碍的一线心理治疗方法。
JAMA. 2020 Feb 18;323(7):656-657. doi: 10.1001/jama.2019.20825.
2
Exploring Nitrous Oxide as Treatment of Mood Disorders: Basic Concepts.探索一氧化二氮作为情绪障碍的治疗方法：基本概念。
J Clin Psychopharmacol. 2018 Apr;38(2):144-148. doi: 10.1097/JCP.0000000000000837.
3
Minimal Clinically Important Differences (MCID) in Assessing Outcomes of Post-Traumatic Stress Disorder.评估创伤后应激障碍结局的最小临床重要差异（MCID）。
Psychiatr Q. 2018 Mar;89(1):141-155. doi: 10.1007/s11126-017-9522-y.
4
The Clinician-Administered PTSD Scale for DSM-5 (CAPS-5): Development and initial psychometric evaluation in military veterans.用于 DSM-5 的临床医生管理 PTSD 量表（CAPS-5）：退伍军人中的开发和初步心理计量评估。
Psychol Assess. 2018 Mar;30(3):383-395. doi: 10.1037/pas0000486. Epub 2017 May 11.
5
It Is Time to Address the Crisis in the Pharmacotherapy of Posttraumatic Stress Disorder: A Consensus Statement of the PTSD Psychopharmacology Working Group.是时候应对创伤后应激障碍药物治疗的危机了：创伤后应激障碍精神药理学工作组的共识声明。
Biol Psychiatry. 2017 Oct 1;82(7):e51-e59. doi: 10.1016/j.biopsych.2017.03.007. Epub 2017 Mar 14.
6
Nitrous oxide speeds the reduction of distressing intrusive memories in an experimental model of psychological trauma.在心理创伤的实验模型中，一氧化二氮加速了令人痛苦的侵入性记忆的消退。
Psychol Med. 2016 Jun;46(8):1749-59. doi: 10.1017/S003329171600026X. Epub 2016 Mar 4.
7
Nitrous Oxide for Treatment-Resistant Major Depression: A Proof-of-Concept Trial.一氧化二氮治疗难治性重度抑郁症：概念验证试验。
Biol Psychiatry. 2015 Jul 1;78(1):10-18. doi: 10.1016/j.biopsych.2014.11.016. Epub 2014 Dec 9.
8
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.静脉注射氯胺酮治疗慢性创伤后应激障碍的疗效：一项随机临床试验。
JAMA Psychiatry. 2014 Jun;71(6):681-8. doi: 10.1001/jamapsychiatry.2014.62.
9
Use of evidence-based treatment for posttraumatic stress disorder in Army behavioral healthcare.在陆军行为保健中使用基于证据的创伤后应激障碍治疗方法。
Psychiatry. 2013 Winter;76(4):336-48. doi: 10.1521/psyc.2013.76.4.336.
10
Practice guideline for the treatment of patients with acute stress disorder and posttraumatic stress disorder.急性应激障碍和创伤后应激障碍患者治疗实践指南。
Am J Psychiatry. 2004 Nov;161(11 Suppl):3-31.

Does Nitrous Oxide Help Veterans With Posttraumatic Stress Disorder? A Case Series.

作者信息

Varias Andrea, van Roessel Peter, Parsiani Maryam, Filippou-Frye Maria, Neylan Thomas C, Nagele Peter, Yesavage Jerome, Clark J David, Rodriguez Carolyn I

机构信息

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California

Veterans Affairs Palo Alto Health Care System, Palo Alto, California

出版信息

J Clin Psychiatry. 2020 Jun 30;81(4):20l13393. doi: 10.4088/JCP.20l13393.

DOI:10.4088/JCP.20l13393
PMID:32609959
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8218879/
Abstract
摘要