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韩国获得性免疫缺陷综合征的历史。

History of Acquired Immune Deficiency Syndrome in Korea.

作者信息

Kim June Myung, Kim Nam Joong, Choi Jun Yong, Chin Bum Sik

机构信息

Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Infect Chemother. 2020 Jun;52(2):234-244. doi: 10.3947/ic.2020.52.2.234.

DOI:10.3947/ic.2020.52.2.234
PMID:32618149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7335645/
Abstract

The first human immunodeficiency virus (HIV) infection was reported in Korea in 1985. The number of HIV-infected persons domestically increased in the 1990s showing epidemic indigenousization. Since then, the number of new infections gradually increased every year, and recently more than 1,000 newly infected cases were reported per year. A total of 12,522 infected individuals have been reported up to 2015, of which 2,020 died. The male to female ratio was 15.4:1, and 34.2% of them were under 30 years old. The infection route was homosexual and bisexual contact in 60.1% of cases and heterosexual contact in 34.6% of cases. Candidiasis, Pneumocystis pneumonia, tuberculosis were common as a AIDS (acquired immune deficiency syndrome)-defining illness. But with the introduction of antiretroviral therapy in the late 1990s, non-AIDS defining illnesses such as metabolic complications, cardiovascular diseases, bone diseases, and neuropsychiatric disorders such as neurocognitive dysfunction, depression, and anxiety are emerging as new health problems. The management policy switched its focus from regulating and monitoring of HIV-infected persons to ensuring access to treatment and promotion of voluntary HIV testing in high-risk groups. Also as the age of the infected persons increases, a need for various supports such as social rehabilitation, life counseling, and welfare has emerged.

摘要

1985年韩国报告了首例人类免疫缺陷病毒(HIV)感染病例。20世纪90年代,韩国国内HIV感染者数量增加,呈现出流行本土化的趋势。从那时起,新感染病例数量逐年逐渐增加,最近每年报告的新感染病例超过1000例。截至2015年,共报告了12522名感染者,其中2020人死亡。男女比例为15.4:1,其中34.2%的感染者年龄在30岁以下。感染途径中,60.1%为同性恋和双性恋接触,34.6%为异性接触。念珠菌病、肺孢子菌肺炎、结核病是常见的艾滋病(获得性免疫缺陷综合征)界定疾病。但随着20世纪90年代末抗逆转录病毒疗法的引入,代谢并发症、心血管疾病、骨骼疾病等非艾滋病界定疾病以及神经认知功能障碍、抑郁症和焦虑症等神经精神疾病正成为新的健康问题。管理政策的重点从对HIV感染者的监管和监测转向确保获得治疗以及促进高危人群自愿进行HIV检测。此外,随着感染者年龄的增加,对社会康复、生活咨询和福利等各种支持的需求也随之出现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c048/7335645/04e5d8c7e065/ic-52-234-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c048/7335645/04e5d8c7e065/ic-52-234-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c048/7335645/04e5d8c7e065/ic-52-234-g001.jpg

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