Chen Yang, Xiao Shu, Huang Jian, Xue Wei, He Shuzhong
Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering Ministry of Education, Guizhou University, Guiyang, China.
Guizhou Engineering Laboratory for Synthetic Drugs, School of Pharmaceutical Sciences, Guizhou University, Guiyang, China.
Front Chem. 2020 Jun 17;8:460. doi: 10.3389/fchem.2020.00460. eCollection 2020.
Haedoxans are a series of sesquilignan natural products isolated from the traditional insecticidal plant . Given their significant insecticidal activity, haedoxans and related analogs have been considered as potential agents for plant defense. Moreover, these compounds also exhibit promising antifungal, antibacterial, and anticancer activities. The present paper is a review of the structure, biological activity, and chemical synthesis of naturally occurring haedoxan-like molecules.
海道烷类化合物是从传统杀虫植物中分离得到的一系列倍半木脂素天然产物。鉴于其显著的杀虫活性,海道烷类化合物及其相关类似物被认为是植物防御的潜在因子。此外,这些化合物还表现出有前景的抗真菌、抗菌和抗癌活性。本文综述了天然存在的类海道烷分子的结构、生物活性及化学合成。