Park Il-Kwon, Shin Sang-Chul, Kim Chul-Su, Lee Hak-Ju, Choi Won-Sil, Ahn Young-Joon
Division of Forest Diseases, Korea Forest Research Institute, Seoul 130-712, Republic of Korea.
J Agric Food Chem. 2005 Feb 23;53(4):969-72. doi: 10.1021/jf048208h.
The insecticidal activity of phytochemicals isolated from the roots of Phryma leptostachya var. asiatica against third instar larvae of Culex pipiens pallens, Aedes aegypti, and Ocheratatos togoi was examined. The two constituents of P. leptostachya var. asiatica roots were identified as the leptostachyol acetate (I) and 8'-acetoxy-2,2',6-trimethoxy-3,4,4',5'-dimethylenedioxyphenyl-7,7'-dioxabicyclo[3.3.0]octane (II) by spectroscopic analysis. Compound I was lethal to C. pipiens pallens, A. aegypti, and O. togoi at 10 ppm. Compound II showed weak or no insecticidal activity against three mosquito species at 10 ppm. The LC(50) values of I against C. pipiens pallens, A. aegypti, and O. togoi were 0.41, 2.1, and 2.3 ppm, respectively. Naturally occurring P. leptostachya var. asiatica root-derived compounds merit further study as potential mosquito larval control agents or lead compounds.
研究了从亚洲排草（Phryma leptostachya var. asiatica）根部分离出的植物化学物质对淡色库蚊（Culex pipiens pallens）、埃及伊蚊（Aedes aegypti）和东乡伊蚊（Ocheratatos togoi）三龄幼虫的杀虫活性。通过光谱分析，将亚洲排草根部的两种成分鉴定为乙酸排草烯醇酯（I）和8'-乙酰氧基-2,2',6-三甲氧基-3,4,4',5'-二亚甲基二氧苯基-7,7'-二氧杂双环[3.3.0]辛烷（II）。化合物I在10 ppm时对淡色库蚊、埃及伊蚊和东乡伊蚊具有致死性。化合物II在10 ppm时对三种蚊虫表现出微弱或无杀虫活性。化合物I对淡色库蚊、埃及伊蚊和东乡伊蚊的LC(50)值分别为0.41、2.1和2.3 ppm。天然存在的亚洲排草根部衍生化合物作为潜在的蚊虫幼虫控制剂或先导化合物值得进一步研究。
