Khlystova Z S, Pospisil M, Rejnek J, Riabchikov O P, Hofman J
Ontogenez. 1988 May-Jun;19(3):327-31.
Data are presented on the spleen and thymus structure, time of appearance of the lymphocytes and their heterogeneity in the liver, thymus, spleen, lymph nodes and blood of human foetuses with hemochorial placenta (3 to 34 weeks) and of the minipigs foetuses with epitheliochorial placenta (32 to 95 days). In both foetuses the first T- and B-lymphocytes are found in liver, T-lymphocytes are then found in thymus and later in spleen and lymph nodes whereas B-lymphocytes are found, after liver, in spleen. Kinetics of T- and B-lymphocytes during embryogenesis is described. Reaction of the minipig lymphocytes to mitogens was demonstrated.
本文呈现了患有血绒毛膜胎盘的人类胎儿（3至34周）以及患有上皮绒毛膜胎盘的小型猪胎儿（32至95天）肝脏、胸腺、脾脏、淋巴结和血液中脾脏和胸腺的结构、淋巴细胞出现的时间及其异质性的数据。在这两种胎儿中，最初的T淋巴细胞和B淋巴细胞在肝脏中被发现，随后T淋巴细胞在胸腺中被发现，之后在脾脏和淋巴结中被发现，而B淋巴细胞在肝脏之后在脾脏中被发现。描述了胚胎发育过程中T淋巴细胞和B淋巴细胞的动力学。还展示了小型猪淋巴细胞对有丝分裂原的反应。
