Gould E S, Bird A C, Leaver P K, McDonald W I
Br Med J. 1977 Jun 11;1(6075):1495-7. doi: 10.1136/bmj.1.6075.1495.
In a single-blind controlled clinical trial patients with optic neuritis caused by demyelination were given a single retrobulbar injection of triamcinolone. Though the treated group showed a trend towards more rapid recovery of vision than the controls, there was no significant difference in visual acuity, colour vision, or visual fields during the first six months after treatment. We conclude that routine use of corticosteroids is not justified in unilateral optic neuritis when vision in the other eye is good. Shortening the period of visual disability in bilateral disease or unilateral disease when vision in the other eye is poor, however, may be justifiable.
在一项单盲对照临床试验中,对患有脱髓鞘性视神经炎的患者进行了一次球后注射曲安奈德。虽然治疗组的视力恢复趋势比对照组更快,但在治疗后的前六个月,视力、色觉或视野方面并无显著差异。我们得出结论,当另一只眼视力良好时,单侧视神经炎常规使用皮质类固醇并不合理。然而,对于双眼疾病或另一只眼视力差的单侧疾病,缩短视力残疾期可能是合理的。