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噬菌体 PaBG-A：古老噬菌体家族的巨型成员。

Phage PaBG-A Jumbo Member of an Old Parasite Family.

机构信息

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.

Limnological Institute, Siberian Branch of Russian Academy of Sciences, 664033 Irkutsk, Russia.

出版信息

Viruses. 2020 Jul 3;12(7):721. doi: 10.3390/v12070721.

DOI:10.3390/v12070721
PMID:32635178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7412058/
Abstract

Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of strains. Therefore, it is hardly suitable for phage therapy applications. However, the analysis of the genome of PaBG presents a number of insights into the evolutionary history of this phage and jumbo phages in general. We suggest that PaBG represents an ancient group distantly related to all known classified families of phages.

摘要

噬菌体现已被广泛应用于治疗多种细菌性疾病。

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