Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Viale Regina Elena 326, Rome, Italy.
Department of Oral and Maxillo Facial Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
Curr Oncol Rep. 2020 Jul 9;22(9):89. doi: 10.1007/s11912-020-00954-3.
This article aims to provide an update on literature data related to mandibular osteoradionecrosis (MORN) secondary to the irradiation of the head and neck region.
Radiotherapy (RT) plays a crucial role in the contemporary management of head and neck cancer (HNC) patients and, despite intensity-modulated technique (IMRT), mandibular osteoradionecrosis (MORN) remains a significant RT-related complication. Based on its clinical manifestation, MORN can negatively affect patients' quality of life. Preventive interventions should be prioritized. This manuscript is expected to represent an opportunity to guide a clear proposal for clinical measures in the individual MORN situations.
本文旨在提供头颈部放疗后下颌骨放射性骨坏死（MORN）相关文献数据的最新更新。
放疗（RT）在头颈部癌症（HNC）患者的现代治疗中起着至关重要的作用，尽管采用了强度调制技术（IMRT），但下颌骨放射性骨坏死（MORN）仍然是一种重要的放疗相关并发症。根据其临床表现，MORN 会对患者的生活质量产生负面影响。应优先采取预防措施。本文旨在为个体 MORN 情况下的临床措施提供明确建议。
