Nilsson-Ehle H, Jagenburg R, Landahl S, Svanborg A, Westin J
Department of Medicine, Ostra Hospital, Gothenburg, Sweden.
Acta Med Scand. 1988;224(6):595-604.
We compared three representative population samples aged 70 (n = 312), 75 (n = 486) and 81 (n = 404) years. Anaemia defined either as blood haemoglobin concentration below the corresponding health-related lower reference limits or according to WHO was, in the total study groups, more common at age 81. Anaemia of unknown cause was rare, but somewhat more common at age 81. Mean blood haemoglobin concentrations in subsamples without definable disorders were significantly lower at age 81 than at ages 70 and 75, whereas the lower health-related reference limits did not differ significantly. White blood cell counts tended to be lower and iron deficiency was somewhat more common at age 81. No significant differences were found in platelet counts or in the prevalence of low plasma cobalamin concentrations. These results indicate a fall in blood haemoglobin with advancing age. The arbitrary WHO criteria for anaemia are clinically applicable at age 70-81.
我们比较了三个具有代表性的人群样本，年龄分别为70岁（n = 312）、75岁（n = 486）和81岁（n = 404）。贫血的定义为血液血红蛋白浓度低于相应的健康相关下限参考值，或根据世界卫生组织的标准，在整个研究组中，81岁时贫血更为常见。不明原因的贫血很少见，但在81岁时略为常见。在无明确疾病的子样本中，81岁时的平均血液血红蛋白浓度显著低于70岁和75岁时，而健康相关的下限参考值没有显著差异。81岁时白细胞计数往往较低，缺铁情况略为常见。血小板计数或低血浆钴胺素浓度的患病率没有显著差异。这些结果表明，随着年龄的增长，血液血红蛋白水平会下降。世界卫生组织关于贫血的任意标准在70 - 81岁时在临床上适用。
