Rush Alzheimer's Disease Center, Rush University Medical Center (CMG, LY, RSW, DAB, PAB), Chicago, IL; Department of Psychiatry and Behavioral Sciences, Rush Medical College (CMG, RSW, PAB), Chicago, IL; Department of Neurological Sciences, Rush Medical College (CMG, LY, RSW, DAB), Chicago, IL.
Rush Alzheimer's Disease Center, Rush University Medical Center (CMG, LY, RSW, DAB, PAB), Chicago, IL; Department of Neurological Sciences, Rush Medical College (CMG, LY, RSW, DAB), Chicago, IL.
Am J Geriatr Psychiatry. 2021 Feb;29(2):117-125. doi: 10.1016/j.jagp.2020.06.010. Epub 2020 Jun 16.
The purpose of this study was to test the hypothesis that late life cognitive activity is associated with decision-making in older adults and to examine whether this association varies by level of cognitive function.
This study employed a cross-sectional design.
All data were collected in participants' community-based residences.
Participants were 1,084 older adults (mean age = 81.05 years, standard deviation = 7.53) without dementia (median Mini-Mental State Examination score = 29, interquartile range = 27.86-30.00).
Participants completed assessments of late life cognitive activity, cognitive function, and decision-making. We used linear regression models to examine the associations of late life cognitive activity and cognitive function with decision-making.
In a regression model adjusted for age, gender, and education, more frequent late life cognitive activity was associated with better decision-making, as was higher cognitive function. Furthermore, in an additional model that included the interaction of late life cognitive activity and cognitive function, the interaction was significant, such that late life cognitive activity was most strongly associated with decision-making among participants with lower levels of cognitive function.
Frequent engagement in late life cognitive activity may help maintain decision-making among older persons, particularly among those with lower levels of cognitive function.
本研究旨在检验假设，即晚年认知活动与老年人的决策相关，并检验这种相关性是否因认知功能水平而异。
本研究采用横断面设计。
所有数据均在参与者的社区居住场所收集。
参与者为 1084 名认知正常的老年人（平均年龄 81.05 岁，标准差 7.53 岁）。（中位数 Mini-Mental State Examination 评分= 29，四分位间距= 27.86-30.00）。
参与者完成了晚年认知活动、认知功能和决策的评估。我们使用线性回归模型来检验晚年认知活动和认知功能与决策的关联。
在调整年龄、性别和教育的回归模型中，更频繁的晚年认知活动与更好的决策相关，认知功能更高也是如此。此外，在包含晚年认知活动和认知功能交互作用的附加模型中，交互作用显著，表明晚年认知活动与认知功能较低的参与者的决策相关性最强。
晚年频繁参与认知活动可能有助于维持老年人的决策能力，尤其是认知功能较低的老年人。
